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A ring-enhancing metastasis with central high signal on diffusion-weighted imaging and low apparent diffusion coefficients

Holtås, Stig LU ; Geijer, Bo LU ; Strömblad, Lars-Göran LU ; Maly, Pavel LU and Björkman-Burtscher, Isabella LU (2000) In Neuroradiology 42(11). p.824-827
Abstract
Diffusion-weighted imaging (DWI) has been reported to be useful in the differential diagnosis between abscesses and cystic or necrotic tumours. However, experience is still limited and the true sensitivity and specificity remain to be determined. Our purpose is to describe a ring-enhancing metastasis of adenocarcinoma with a DWI pattern similar to that reported for abscesses. The tumour had a diameter of 1.5 cm and give signal from its centre similar to that of normal brain on T1-weighted images, whereas it was increased on T2-weighted images, and surrounded by a low signal ring, suggesting a capsule. The signal was high on DWI and the apparent diffusion coefficient (ADC) was low (0.55 x 10(-3) mm2/s). The findings were misinterpreted as... (More)
Diffusion-weighted imaging (DWI) has been reported to be useful in the differential diagnosis between abscesses and cystic or necrotic tumours. However, experience is still limited and the true sensitivity and specificity remain to be determined. Our purpose is to describe a ring-enhancing metastasis of adenocarcinoma with a DWI pattern similar to that reported for abscesses. The tumour had a diameter of 1.5 cm and give signal from its centre similar to that of normal brain on T1-weighted images, whereas it was increased on T2-weighted images, and surrounded by a low signal ring, suggesting a capsule. The signal was high on DWI and the apparent diffusion coefficient (ADC) was low (0.55 x 10(-3) mm2/s). The findings were misinterpreted as representing an abscess in the early capsule-formation stage, but the signal pattern probably represented early tumour necrosis with intracellular oedema, but without liquefaction. Findings on DWI during the early capsule formation stage in abscesses and early tumour necrosis are probably similar and must be interpreted with caution. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
magnetic resonance imaging, diffusion-weighted, abscess, brain, tumour
in
Neuroradiology
volume
42
issue
11
pages
824 - 827
publisher
Springer Verlag
external identifiers
  • pmid:11151689
  • scopus:0033675714
ISSN
1432-1920
DOI
10.1007/s002340000431
language
English
LU publication?
yes
id
134f49f7-321b-4653-a2c3-e2a3ff8bb69d (old id 1117351)
date added to LUP
2008-07-03 11:24:34
date last changed
2017-06-25 03:34:13
@article{134f49f7-321b-4653-a2c3-e2a3ff8bb69d,
  abstract     = {Diffusion-weighted imaging (DWI) has been reported to be useful in the differential diagnosis between abscesses and cystic or necrotic tumours. However, experience is still limited and the true sensitivity and specificity remain to be determined. Our purpose is to describe a ring-enhancing metastasis of adenocarcinoma with a DWI pattern similar to that reported for abscesses. The tumour had a diameter of 1.5 cm and give signal from its centre similar to that of normal brain on T1-weighted images, whereas it was increased on T2-weighted images, and surrounded by a low signal ring, suggesting a capsule. The signal was high on DWI and the apparent diffusion coefficient (ADC) was low (0.55 x 10(-3) mm2/s). The findings were misinterpreted as representing an abscess in the early capsule-formation stage, but the signal pattern probably represented early tumour necrosis with intracellular oedema, but without liquefaction. Findings on DWI during the early capsule formation stage in abscesses and early tumour necrosis are probably similar and must be interpreted with caution.},
  author       = {Holtås, Stig and Geijer, Bo and Strömblad, Lars-Göran and Maly, Pavel and Björkman-Burtscher, Isabella},
  issn         = {1432-1920},
  keyword      = {magnetic resonance imaging,diffusion-weighted,abscess,brain,tumour},
  language     = {eng},
  number       = {11},
  pages        = {824--827},
  publisher    = {Springer Verlag},
  series       = {Neuroradiology},
  title        = {A ring-enhancing metastasis with central high signal on diffusion-weighted imaging and low apparent diffusion coefficients},
  url          = {http://dx.doi.org/10.1007/s002340000431},
  volume       = {42},
  year         = {2000},
}