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Long-term risk of osteoporotic fracture in Malmo

Kanis, J A; Johnell, Olof LU ; Oden, A; Sernbo, Ingemar LU ; Redlund-Johnell, Inga LU ; Dawson, A; De Laet, C and Jonsson, B (2000) In Osteoporosis International 11(8). p.669-674
Abstract
The objectives of the present study were to estimate long-term risks of osteoporotic fractures. The incidence of hip, distal forearm, proximal humerus and vertebral fracture were obtained from patient records in Malmo, Sweden. Vertebral fractures were confined to those coming to clinical attention, either as an inpatient or an outpatient case. Patient records were examined to exclude individuals with prior fractures at the same site. Future mortality rates were computed for each year of age from Poisson models using the Swedish Patient Register and the Statistical Year Book. The incidence and lifetime risk of any fracture were determined from the proportion of individuals fracture-free from the age of 45 years. Lifetime risk of shoulder,... (More)
The objectives of the present study were to estimate long-term risks of osteoporotic fractures. The incidence of hip, distal forearm, proximal humerus and vertebral fracture were obtained from patient records in Malmo, Sweden. Vertebral fractures were confined to those coming to clinical attention, either as an inpatient or an outpatient case. Patient records were examined to exclude individuals with prior fractures at the same site. Future mortality rates were computed for each year of age from Poisson models using the Swedish Patient Register and the Statistical Year Book. The incidence and lifetime risk of any fracture were determined from the proportion of individuals fracture-free from the age of 45 years. Lifetime risk of shoulder, forearm, hip and spine fracture were 13.3%, 21.5%, 23.3% and 15.4% respectively in women at the age of 45 years. Corresponding values for men at the age of 45 years were 4.4%, 5.2%, 11.2% and 8.6%. The risk of any of these fractures was 47.3% and 23.8% in women and men respectively. Remaining lifetime risk was stable with age for hip fracture, but decreased by 20-30% by the age of 70 years in the case of other fractures. Ten and 15 year risks for all types of fractures increased with age until the age of 80 years, when they approached lifetime risks because of the competing probabilities of fracture and death. We conclude that fractures of the hip and spine carry higher risks than fractures at other sites, and that lifetime risks of fracture of the hip in particular have been underestimated. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Osteoporosis International
volume
11
issue
8
pages
669 - 674
publisher
Springer
external identifiers
  • pmid:11095169
  • scopus:0033793450
ISSN
1433-2965
DOI
10.1007/s001980070064
language
English
LU publication?
yes
id
a09c2a88-6e0d-4c68-9e5a-2256687c372a (old id 1117384)
date added to LUP
2008-06-27 14:45:40
date last changed
2017-11-19 04:03:15
@article{a09c2a88-6e0d-4c68-9e5a-2256687c372a,
  abstract     = {The objectives of the present study were to estimate long-term risks of osteoporotic fractures. The incidence of hip, distal forearm, proximal humerus and vertebral fracture were obtained from patient records in Malmo, Sweden. Vertebral fractures were confined to those coming to clinical attention, either as an inpatient or an outpatient case. Patient records were examined to exclude individuals with prior fractures at the same site. Future mortality rates were computed for each year of age from Poisson models using the Swedish Patient Register and the Statistical Year Book. The incidence and lifetime risk of any fracture were determined from the proportion of individuals fracture-free from the age of 45 years. Lifetime risk of shoulder, forearm, hip and spine fracture were 13.3%, 21.5%, 23.3% and 15.4% respectively in women at the age of 45 years. Corresponding values for men at the age of 45 years were 4.4%, 5.2%, 11.2% and 8.6%. The risk of any of these fractures was 47.3% and 23.8% in women and men respectively. Remaining lifetime risk was stable with age for hip fracture, but decreased by 20-30% by the age of 70 years in the case of other fractures. Ten and 15 year risks for all types of fractures increased with age until the age of 80 years, when they approached lifetime risks because of the competing probabilities of fracture and death. We conclude that fractures of the hip and spine carry higher risks than fractures at other sites, and that lifetime risks of fracture of the hip in particular have been underestimated.},
  author       = {Kanis, J A and Johnell, Olof and Oden, A and Sernbo, Ingemar and Redlund-Johnell, Inga and Dawson, A and De Laet, C and Jonsson, B},
  issn         = {1433-2965},
  language     = {eng},
  number       = {8},
  pages        = {669--674},
  publisher    = {Springer},
  series       = {Osteoporosis International},
  title        = {Long-term risk of osteoporotic fracture in Malmo},
  url          = {http://dx.doi.org/10.1007/s001980070064},
  volume       = {11},
  year         = {2000},
}