Platelet retention in coronary artery bypass surgery with and without a heart-lung machine. Cause of thrombosis in coronary artery bypass surgery
(2000) In Scandinavian Cardiovascular Journal 34(3). p.301-306- Abstract
- The aim of this study was to examine platelet function after coronary artery bypass grafting (CABG) with and without the use of extracorporeal circulation (ECC). Sixteen male patients scheduled for CABG with (n = 8) and without (n = 8) ECC were included in the study. Platelet retention, as measured with a glass-bead retention test, was examined daily during the first postoperative week. Von Willebrand factor (vWF), ristocetin co-factor (Rcof) and prothrombin fragment (PF 1 + 2) were analyzed the day after the operation. We found a significant increase (p < 0.0001) in platelet retention during the first postoperative week after CABG. There was a tendency (not statistically significant) towards a more pronounced increase in the group... (More)
- The aim of this study was to examine platelet function after coronary artery bypass grafting (CABG) with and without the use of extracorporeal circulation (ECC). Sixteen male patients scheduled for CABG with (n = 8) and without (n = 8) ECC were included in the study. Platelet retention, as measured with a glass-bead retention test, was examined daily during the first postoperative week. Von Willebrand factor (vWF), ristocetin co-factor (Rcof) and prothrombin fragment (PF 1 + 2) were analyzed the day after the operation. We found a significant increase (p < 0.0001) in platelet retention during the first postoperative week after CABG. There was a tendency (not statistically significant) towards a more pronounced increase in the group operated on without ECC. This increase occurred despite the fact that all patients were treated with aspirin (75 mg daily) from the first postoperative day. The median time to maximal postoperative platelet retention was 2 days. In 3 patients platelet retention increased to more than 6 times the basal level. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1118363
- author
- Samuelsson Palmgren, Gabriella LU ; Lindgren, Anna ; Lethagen, Stefan LU and Steen, Stig LU
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Cardiovascular Journal
- volume
- 34
- issue
- 3
- pages
- 301 - 306
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:10935778
- scopus:0034207642
- ISSN
- 1651-2006
- DOI
- 10.1080/713783111
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Thoracic Surgery (013230027), Anaesthesiology and Intensive Care (013230022), Emergency medicine/Medicine/Surgery (013240200)
- id
- 38f6398f-acb1-470f-afe1-d7bfc54d9417 (old id 1118363)
- date added to LUP
- 2016-04-01 16:22:49
- date last changed
- 2022-01-28 19:17:46
@article{38f6398f-acb1-470f-afe1-d7bfc54d9417, abstract = {{The aim of this study was to examine platelet function after coronary artery bypass grafting (CABG) with and without the use of extracorporeal circulation (ECC). Sixteen male patients scheduled for CABG with (n = 8) and without (n = 8) ECC were included in the study. Platelet retention, as measured with a glass-bead retention test, was examined daily during the first postoperative week. Von Willebrand factor (vWF), ristocetin co-factor (Rcof) and prothrombin fragment (PF 1 + 2) were analyzed the day after the operation. We found a significant increase (p < 0.0001) in platelet retention during the first postoperative week after CABG. There was a tendency (not statistically significant) towards a more pronounced increase in the group operated on without ECC. This increase occurred despite the fact that all patients were treated with aspirin (75 mg daily) from the first postoperative day. The median time to maximal postoperative platelet retention was 2 days. In 3 patients platelet retention increased to more than 6 times the basal level.}}, author = {{Samuelsson Palmgren, Gabriella and Lindgren, Anna and Lethagen, Stefan and Steen, Stig}}, issn = {{1651-2006}}, language = {{eng}}, number = {{3}}, pages = {{301--306}}, publisher = {{Taylor & Francis}}, series = {{Scandinavian Cardiovascular Journal}}, title = {{Platelet retention in coronary artery bypass surgery with and without a heart-lung machine. Cause of thrombosis in coronary artery bypass surgery}}, url = {{http://dx.doi.org/10.1080/713783111}}, doi = {{10.1080/713783111}}, volume = {{34}}, year = {{2000}}, }