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Magnetic resonance imaging of the knee in chronic knee pain. A 2-year follow-up

Boegard, T.L.; Rudling, O.; Petersson, Ingemar LU and Jonsson, Kjell LU (2001) In Osteoarthritis and Cartilage 9(5). p.473-480
Abstract
Objective: The aim of the study was to evaluate the change over time of cartilage defects, subchondral lesions and meniscal abnormalities of the knee using magnetic resonance (MR) imaging with a 2-year interval in patients with chronic knee pain. Design: In the format of a prospective study of early osteoarthritis (OA), the signal knee (most painful at the inclusion in the study 1990) in 47 individuals, 25 women and 22 men (aged 41-57 years, median 50), with chronic knee pain, with or without radiographically determined knee OA, were examined using MR imaging on a 1.0 T imager with a 2-year interval (median 25 months, range 21-30). Cartilage defects, subchondral lesions and meniscal abnormalities were recorded and compared in blind between... (More)
Objective: The aim of the study was to evaluate the change over time of cartilage defects, subchondral lesions and meniscal abnormalities of the knee using magnetic resonance (MR) imaging with a 2-year interval in patients with chronic knee pain. Design: In the format of a prospective study of early osteoarthritis (OA), the signal knee (most painful at the inclusion in the study 1990) in 47 individuals, 25 women and 22 men (aged 41-57 years, median 50), with chronic knee pain, with or without radiographically determined knee OA, were examined using MR imaging on a 1.0 T imager with a 2-year interval (median 25 months, range 21-30). Cartilage defects, subchondral lesions and meniscal abnormalities were recorded and compared in blind between the examinations. Results: Five new cartilage defects and eight subchondral lesions appeared during the 2-year interval. Seven defects and seven subchondral lesions disappeared during the same time. Thirty-two out of 93 cartilage defects (34%) and 19 out of 32 subchondral lesions (59%) displayed an increase or a decrease in size over time. A meniscal abnormality appeared in three locations, and disappeared in none. In 14 out of 54 locations (26%) with a meniscal abnormality an increase or a decrease of the abnormality was recorded over time and no abnormality decreased. Conclusions: After the 2 years of observation it was possible to register, using MR imaging, the appearance, increase, decrease and disappearance of cartilage defects, subchondral lesions and meniscal abnormalities in middle-aged people with chronic knee pain. This has to be considered in studies of the natural course of knee CA as well as in studies of the intraarticular effect of pharmacological treatment aiming at cartilage repair or protection. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
MR imaging, Osteoarthritis, Knee pain, Follow-up studies
in
Osteoarthritis and Cartilage
volume
9
issue
5
pages
473 - 480
publisher
Elsevier
external identifiers
  • wos:000170254400010
  • scopus:0034902108
ISSN
1063-4584
DOI
10.1053/joca.2001.0414
language
English
LU publication?
yes
id
beced003-a50e-4c5e-a239-c170a52ea0bc (old id 1119016)
date added to LUP
2008-06-25 11:49:43
date last changed
2018-05-29 09:44:01
@article{beced003-a50e-4c5e-a239-c170a52ea0bc,
  abstract     = {Objective: The aim of the study was to evaluate the change over time of cartilage defects, subchondral lesions and meniscal abnormalities of the knee using magnetic resonance (MR) imaging with a 2-year interval in patients with chronic knee pain. Design: In the format of a prospective study of early osteoarthritis (OA), the signal knee (most painful at the inclusion in the study 1990) in 47 individuals, 25 women and 22 men (aged 41-57 years, median 50), with chronic knee pain, with or without radiographically determined knee OA, were examined using MR imaging on a 1.0 T imager with a 2-year interval (median 25 months, range 21-30). Cartilage defects, subchondral lesions and meniscal abnormalities were recorded and compared in blind between the examinations. Results: Five new cartilage defects and eight subchondral lesions appeared during the 2-year interval. Seven defects and seven subchondral lesions disappeared during the same time. Thirty-two out of 93 cartilage defects (34%) and 19 out of 32 subchondral lesions (59%) displayed an increase or a decrease in size over time. A meniscal abnormality appeared in three locations, and disappeared in none. In 14 out of 54 locations (26%) with a meniscal abnormality an increase or a decrease of the abnormality was recorded over time and no abnormality decreased. Conclusions: After the 2 years of observation it was possible to register, using MR imaging, the appearance, increase, decrease and disappearance of cartilage defects, subchondral lesions and meniscal abnormalities in middle-aged people with chronic knee pain. This has to be considered in studies of the natural course of knee CA as well as in studies of the intraarticular effect of pharmacological treatment aiming at cartilage repair or protection.},
  author       = {Boegard, T.L. and Rudling, O. and Petersson, Ingemar and Jonsson, Kjell},
  issn         = {1063-4584},
  keyword      = {MR imaging,Osteoarthritis,Knee pain,Follow-up studies},
  language     = {eng},
  number       = {5},
  pages        = {473--480},
  publisher    = {Elsevier},
  series       = {Osteoarthritis and Cartilage},
  title        = {Magnetic resonance imaging of the knee in chronic knee pain. A 2-year follow-up},
  url          = {http://dx.doi.org/10.1053/joca.2001.0414},
  volume       = {9},
  year         = {2001},
}