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Quality of life in palliative cancer care: results from a cluster randomized trial

Jordhoy, Marit S.; Fayers, Peter; Loge, Jon Håvard; Ahlner-Elmqvist, Marianne LU and Kaasa, Stein (2001) In Journal of Clinical Oncology 19(18). p.3884-3894
Abstract
PURPOSE: To assess the impact of comprehensive palliative care on patients' quality of life. The intervention was based on cooperation between a palliative medicine unit and the community service and was compared with conventional care. PATIENTS AND METHODS: A cluster randomized trial was carried out, with community health care districts defined as the clusters. Patients from these districts who had malignant disease and survival expectancy between 2 to 9 months were entered onto the trial. The main quality-of-life end points were physical and emotional functioning, pain, and psychologic distress assessed monthly by using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30)... (More)
PURPOSE: To assess the impact of comprehensive palliative care on patients' quality of life. The intervention was based on cooperation between a palliative medicine unit and the community service and was compared with conventional care. PATIENTS AND METHODS: A cluster randomized trial was carried out, with community health care districts defined as the clusters. Patients from these districts who had malignant disease and survival expectancy between 2 to 9 months were entered onto the trial. The main quality-of-life end points were physical and emotional functioning, pain, and psychologic distress assessed monthly by using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) questionnaire and Impact of Event scale (IES). In total, 235 intervention patients and 199 controls were included. RESULTS: During the initial 4 months of follow-up, the compliance was good (72%) and comparable among treatment groups. No significant differences on any of the quality-of-life scores were found. At later assessments and for scores that were made within 3 months before death, there was also no consistent tendency in favor of any treatment group on the main outcomes or other EORTC QLQ-C30 scales/items. CONCLUSION: A general program of palliative care may be important to ensure flexibility and to meet the needs of terminally ill patients. However, to achieve improvements on a group level of the various dimensions of quality of life, specific interventions directed toward specific symptoms or problems may have to be defined, evaluated, and included in the program. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Oncology
volume
19
issue
18
pages
3884 - 3894
publisher
American Society of Clinical Oncology
external identifiers
  • pmid:11559726
  • scopus:0035884433
ISSN
1527-7755
language
English
LU publication?
yes
id
ddb4beaa-ccb9-42ab-b70c-c7ab322279e4 (old id 1120647)
alternative location
http://jco.ascopubs.org/cgi/reprint/19/18/3884
date added to LUP
2008-07-01 10:38:32
date last changed
2018-05-29 10:46:11
@article{ddb4beaa-ccb9-42ab-b70c-c7ab322279e4,
  abstract     = {PURPOSE: To assess the impact of comprehensive palliative care on patients' quality of life. The intervention was based on cooperation between a palliative medicine unit and the community service and was compared with conventional care. PATIENTS AND METHODS: A cluster randomized trial was carried out, with community health care districts defined as the clusters. Patients from these districts who had malignant disease and survival expectancy between 2 to 9 months were entered onto the trial. The main quality-of-life end points were physical and emotional functioning, pain, and psychologic distress assessed monthly by using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) questionnaire and Impact of Event scale (IES). In total, 235 intervention patients and 199 controls were included. RESULTS: During the initial 4 months of follow-up, the compliance was good (72%) and comparable among treatment groups. No significant differences on any of the quality-of-life scores were found. At later assessments and for scores that were made within 3 months before death, there was also no consistent tendency in favor of any treatment group on the main outcomes or other EORTC QLQ-C30 scales/items. CONCLUSION: A general program of palliative care may be important to ensure flexibility and to meet the needs of terminally ill patients. However, to achieve improvements on a group level of the various dimensions of quality of life, specific interventions directed toward specific symptoms or problems may have to be defined, evaluated, and included in the program.},
  author       = {Jordhoy, Marit S. and Fayers, Peter and Loge, Jon Håvard and Ahlner-Elmqvist, Marianne and Kaasa, Stein},
  issn         = {1527-7755},
  language     = {eng},
  number       = {18},
  pages        = {3884--3894},
  publisher    = {American Society of Clinical Oncology},
  series       = {Journal of Clinical Oncology},
  title        = {Quality of life in palliative cancer care: results from a cluster randomized trial},
  volume       = {19},
  year         = {2001},
}