Advanced

A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter

Gustafsson, Mattias LU and von Wachenfeldt, Claes LU (2001) In FEMS Microbiology Letters 199(2). p.197-202
Abstract
In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cytochrome P450, AbrB, FatR, Bacillus subtilis
in
FEMS Microbiology Letters
volume
199
issue
2
pages
197 - 202
publisher
Elsevier
external identifiers
  • pmid:11377867
  • scopus:0035972878
ISSN
1574-6968
DOI
10.1016/S0378-1097(01)00177-X
language
English
LU publication?
yes
id
01a7e67e-cf02-4154-92cd-319c308c5c75 (old id 1121791)
date added to LUP
2008-06-30 10:28:06
date last changed
2018-01-07 09:40:23
@article{01a7e67e-cf02-4154-92cd-319c308c5c75,
  abstract     = {In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.},
  author       = {Gustafsson, Mattias and von Wachenfeldt, Claes},
  issn         = {1574-6968},
  keyword      = {Cytochrome P450,AbrB,FatR,Bacillus subtilis},
  language     = {eng},
  number       = {2},
  pages        = {197--202},
  publisher    = {Elsevier},
  series       = {FEMS Microbiology Letters},
  title        = {A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter},
  url          = {http://dx.doi.org/10.1016/S0378-1097(01)00177-X},
  volume       = {199},
  year         = {2001},
}