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Impaired glucose metabolism and obesity in Swedish patients with borderline isolated systolic hypertension: Skaraborg Hypertension and Diabetes Project

Bøg-Hansen, Erik LU ; Lindblad, Ulf LU ; Ranstam, J; Melander, Arne LU and Råstam, Lennart LU (2001) In Diabetes, Obesity and Metabolism 3(1). p.25-31
Abstract
AIM: To assess the prevalence of borderline isolated systolic hypertension (borderline ISH), and to examine its association with other cardiovascular risk factors. METHODS: A cross-sectional community-based study was carried out in 1993-1994 in Skara, Sweden, including 1109 randomly chosen subjects > or = 40 years old. Normotension (NT) was defined as systolic blood pressure (SBP) < 140 and diastolic blood pressure (DBP) < 90 mmHg, borderline ISH as SBP 140-159 and DBP < 90 mmHg and hypertension (HT) as SBP > or = 160 or DBP > or = 90 mmHg or ongoing treatment. RESULTS: The prevalence of borderline ISH (n = 203) by age was 4% in ages 40-49 years, 15% in ages 50-59 years, 28% in ages 60-69 years and 25% in ages 70-79... (More)
AIM: To assess the prevalence of borderline isolated systolic hypertension (borderline ISH), and to examine its association with other cardiovascular risk factors. METHODS: A cross-sectional community-based study was carried out in 1993-1994 in Skara, Sweden, including 1109 randomly chosen subjects > or = 40 years old. Normotension (NT) was defined as systolic blood pressure (SBP) < 140 and diastolic blood pressure (DBP) < 90 mmHg, borderline ISH as SBP 140-159 and DBP < 90 mmHg and hypertension (HT) as SBP > or = 160 or DBP > or = 90 mmHg or ongoing treatment. RESULTS: The prevalence of borderline ISH (n = 203) by age was 4% in ages 40-49 years, 15% in ages 50-59 years, 28% in ages 60-69 years and 25% in ages 70-79 years. With borderline ISH as reference, normotensive subjects less often had fasting blood glucose > 5.5 mmol/l (odds ratio (OR): 0.4, 95% CI: 0.26-0.75), BMI > 27 kg/m2 (OR: 0.6, 95% confidence intervals (CI): 0.42-0.85) and known diabetes (OR: 0.4, 95% CI: 0.16-0.95). Hypertensive subjects more often had high density lipoprotein (HDL) cholesterol < 1.0 mmol/l (OR: 2.0, 95% CI: 1.35-2.99), a history of previous cardiovascular disease (CVD) (OR: 1.7, 95% CI: 1.01-2.72), known diabetes (OR: 2.4, 95% CI: 1.29-4.58) and microalbuminuria (men) (OR: 1.9, 95% CI: 1.15-3.11). CONCLUSION: Borderline ISH is a common condition. It is associated with a more unfavourable risk factor profile than that of normotensive subjects concerning primarily glucose metabolism and obesity. The prevalence of known diabetes increased with the degree of hypertension. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
primary health care, borderline isolated systolic hypertension, diabetes, obesity
in
Diabetes, Obesity and Metabolism
volume
3
issue
1
pages
25 - 31
publisher
Wiley-Blackwell
external identifiers
  • pmid:11213596
  • scopus:0034875190
ISSN
1462-8902
DOI
10.1046/j.1463-1326.2001.00097.x
language
English
LU publication?
yes
id
c01b59ae-943d-4ac4-8e1c-93b36117dd5e (old id 1122710)
date added to LUP
2008-06-25 11:54:25
date last changed
2018-06-10 03:44:10
@article{c01b59ae-943d-4ac4-8e1c-93b36117dd5e,
  abstract     = {AIM: To assess the prevalence of borderline isolated systolic hypertension (borderline ISH), and to examine its association with other cardiovascular risk factors. METHODS: A cross-sectional community-based study was carried out in 1993-1994 in Skara, Sweden, including 1109 randomly chosen subjects &gt; or = 40 years old. Normotension (NT) was defined as systolic blood pressure (SBP) &lt; 140 and diastolic blood pressure (DBP) &lt; 90 mmHg, borderline ISH as SBP 140-159 and DBP &lt; 90 mmHg and hypertension (HT) as SBP &gt; or = 160 or DBP &gt; or = 90 mmHg or ongoing treatment. RESULTS: The prevalence of borderline ISH (n = 203) by age was 4% in ages 40-49 years, 15% in ages 50-59 years, 28% in ages 60-69 years and 25% in ages 70-79 years. With borderline ISH as reference, normotensive subjects less often had fasting blood glucose &gt; 5.5 mmol/l (odds ratio (OR): 0.4, 95% CI: 0.26-0.75), BMI &gt; 27 kg/m2 (OR: 0.6, 95% confidence intervals (CI): 0.42-0.85) and known diabetes (OR: 0.4, 95% CI: 0.16-0.95). Hypertensive subjects more often had high density lipoprotein (HDL) cholesterol &lt; 1.0 mmol/l (OR: 2.0, 95% CI: 1.35-2.99), a history of previous cardiovascular disease (CVD) (OR: 1.7, 95% CI: 1.01-2.72), known diabetes (OR: 2.4, 95% CI: 1.29-4.58) and microalbuminuria (men) (OR: 1.9, 95% CI: 1.15-3.11). CONCLUSION: Borderline ISH is a common condition. It is associated with a more unfavourable risk factor profile than that of normotensive subjects concerning primarily glucose metabolism and obesity. The prevalence of known diabetes increased with the degree of hypertension.},
  author       = {Bøg-Hansen, Erik and Lindblad, Ulf and Ranstam, J and Melander, Arne and Råstam, Lennart},
  issn         = {1462-8902},
  keyword      = {primary health care,borderline isolated systolic hypertension,diabetes,obesity},
  language     = {eng},
  number       = {1},
  pages        = {25--31},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetes, Obesity and Metabolism},
  title        = {Impaired glucose metabolism and obesity in Swedish patients with borderline isolated systolic hypertension: Skaraborg Hypertension and Diabetes Project},
  url          = {http://dx.doi.org/10.1046/j.1463-1326.2001.00097.x},
  volume       = {3},
  year         = {2001},
}