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Blood velocity in the fetal vein of Galen and the outcome of high-risk pregnancy

Dubiel, Mariusz; Breborowicz, Grzegorz H.; Laurini, Ricardo LU and Gudmundsson, Saemundur LU (2001) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 99(1). p.14-18
Abstract
BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood... (More)
BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood flow velocity waveform were also recorded at the same time. The clinicians managing the women were unaware of the venous flow results. RESULTS: Pulsation were present in the vein of Galen in 68 cases and in the umbilical vein in 21. Both were significantly related to adverse outcome. Pulsations in the vein of Galen were seen in all seven perinatal deaths. CONCLUSIONS: Since umbilical venous pulsation are a late sign of fetal compromise, and pulsations in the vein of Galen seem to appear earlier, thus being an intermediate sign of fetal compromise that might be of great value for fetal surveillance. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Vein of Galen, Doppler ultrasound, Umbilical vein, Pregnancy
in
European Journal of Obstetrics, Gynecology, and Reproductive Biology
volume
99
issue
1
pages
14 - 18
publisher
Elsevier
external identifiers
  • pmid:11604180
  • scopus:0034790772
ISSN
0301-2115
DOI
10.1016/S0301-2115(01)00340-2
language
English
LU publication?
yes
id
1f826e2a-264d-460d-8977-f9d8fcdbaf3c (old id 1122990)
date added to LUP
2008-06-26 13:37:19
date last changed
2018-01-07 06:00:03
@article{1f826e2a-264d-460d-8977-f9d8fcdbaf3c,
  abstract     = {BACKGROUND: Pulsation in the flow velocity waveform in the umbilical vein is related to perinatal mortality but the flow velocity waveform in the fetal vein of Galen is normally even and without fluctuation. OBJECTIVES: To establish whether blood flow velocity pulsations in the vein of Galen in high-risk pregnancies are related to outcome. STUDY DESIGN: The vein of Galen was located by colour Doppler ultrasound in 102 pregnancies complicated by severe pregnancy-induced hypertension. The blood velocity waveform was recorded by pulsed Doppler within 2 days of delivery and the presence pulsations related to pregnancy outcome, including emergency operative intervention and neonatal distress. Umbilical artery and vein and uterine artery blood flow velocity waveform were also recorded at the same time. The clinicians managing the women were unaware of the venous flow results. RESULTS: Pulsation were present in the vein of Galen in 68 cases and in the umbilical vein in 21. Both were significantly related to adverse outcome. Pulsations in the vein of Galen were seen in all seven perinatal deaths. CONCLUSIONS: Since umbilical venous pulsation are a late sign of fetal compromise, and pulsations in the vein of Galen seem to appear earlier, thus being an intermediate sign of fetal compromise that might be of great value for fetal surveillance.},
  author       = {Dubiel, Mariusz and Breborowicz, Grzegorz H. and Laurini, Ricardo and Gudmundsson, Saemundur},
  issn         = {0301-2115},
  keyword      = {Vein of Galen,Doppler ultrasound,Umbilical vein,Pregnancy},
  language     = {eng},
  number       = {1},
  pages        = {14--18},
  publisher    = {Elsevier},
  series       = {European Journal of Obstetrics, Gynecology, and Reproductive Biology},
  title        = {Blood velocity in the fetal vein of Galen and the outcome of high-risk pregnancy},
  url          = {http://dx.doi.org/10.1016/S0301-2115(01)00340-2},
  volume       = {99},
  year         = {2001},
}