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Anti-infective effects o Lactobacilli in the gastrointestinal tract

Thorlacius, Henrik LU and Jeppsson, Bengt LU (2003) In Current Medicinal Chemistry - Anti-Infective Agents 2(4). p.263-267
Abstract
Antibiotics constitute the dominant treatment of gastrointestinal infections. However, several serious side-effects are associated with extensive use of antibiotics, including spread of bacterial resistance and allergic reactions as well as potential overgrowth of pathogenic bacteria and viruses. On the other hand, there is a growing body of evidence suggesting that certain bacteria, referred to as probiotics, have anti-bacterial properties and may counteract the development of infections. Probiotics are defined as viable non-pathogenic microorganisms, which, upon ingestion exert a positive impact in the host. This review will focus on the antiinfective mechanisms and effects of lactobacilli and suggests that administration of lactobacilli... (More)
Antibiotics constitute the dominant treatment of gastrointestinal infections. However, several serious side-effects are associated with extensive use of antibiotics, including spread of bacterial resistance and allergic reactions as well as potential overgrowth of pathogenic bacteria and viruses. On the other hand, there is a growing body of evidence suggesting that certain bacteria, referred to as probiotics, have anti-bacterial properties and may counteract the development of infections. Probiotics are defined as viable non-pathogenic microorganisms, which, upon ingestion exert a positive impact in the host. This review will focus on the antiinfective mechanisms and effects of lactobacilli and suggests that administration of lactobacilli may be an effective approach to prevent and treat a vast spectrum of infections of enteric origin. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
infection, probiotics, gastrointestinal tract, lactobacilli
in
Current Medicinal Chemistry - Anti-Infective Agents
volume
2
issue
4
pages
263 - 267
publisher
Bentham Science Publishers
ISSN
1568-0126
language
English
LU publication?
yes
id
ece1e52a-5972-4b50-a6f5-d24d1038dfb1 (old id 1127692)
date added to LUP
2008-06-05 11:13:52
date last changed
2016-09-30 05:52:26
@article{ece1e52a-5972-4b50-a6f5-d24d1038dfb1,
  abstract     = {Antibiotics constitute the dominant treatment of gastrointestinal infections. However, several serious side-effects are associated with extensive use of antibiotics, including spread of bacterial resistance and allergic reactions as well as potential overgrowth of pathogenic bacteria and viruses. On the other hand, there is a growing body of evidence suggesting that certain bacteria, referred to as probiotics, have anti-bacterial properties and may counteract the development of infections. Probiotics are defined as viable non-pathogenic microorganisms, which, upon ingestion exert a positive impact in the host. This review will focus on the antiinfective mechanisms and effects of lactobacilli and suggests that administration of lactobacilli may be an effective approach to prevent and treat a vast spectrum of infections of enteric origin.},
  author       = {Thorlacius, Henrik and Jeppsson, Bengt},
  issn         = {1568-0126},
  keyword      = {infection,probiotics,gastrointestinal tract,lactobacilli},
  language     = {eng},
  number       = {4},
  pages        = {263--267},
  publisher    = {Bentham Science Publishers},
  series       = {Current Medicinal Chemistry - Anti-Infective Agents},
  title        = {Anti-infective effects o Lactobacilli in the gastrointestinal tract},
  volume       = {2},
  year         = {2003},
}