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A controlled study of tryptophan and cortisol in violent offenders

Anckarsäter, Henrik LU ; Blennow, Kaj LU ; Forsman, A; Liesivuori, J; Pennanen, S and Tiihonen, J (2004) In Journal of Neural Transmission 111(12). p.1605-1610
Abstract
Changes in the metabolism of tryptophan, other amino acids, and steroid hormones have been implicated in aggression. We compared tryptophan, competing long amino acids (CAAs), and cortisol in serum (S) and CSF in 22 violent offenders and 15 healthy controls. Offenders had significantly increased S-L-tryptophan, S-free tryptophan, S-CAAs, S-cortisol and CSF-cortisol, indicating abnormal neurophysiological processes. Larger studies on the interplay between violence, serotonin precursors, and stress hormones need to integrate personality traits, life situations, and physiological adaptation.
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Forensic psychiatry, violent behavior, serotonin, cortisol
in
Journal of Neural Transmission
volume
111
issue
12
pages
1605 - 1610
publisher
Springer
external identifiers
  • pmid:15565494
  • scopus:11244267199
ISSN
0300-9564
DOI
10.1007/s00702-004-0219-7
language
English
LU publication?
no
id
5f4c39a1-e0c1-4caa-9b63-2beb42ca87bd (old id 1129366)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/15565494
http://link.springer.com/article/10.1007%2Fs00702-004-0219-7
date added to LUP
2013-10-10 15:02:56
date last changed
2017-01-01 07:05:52
@article{5f4c39a1-e0c1-4caa-9b63-2beb42ca87bd,
  abstract     = {Changes in the metabolism of tryptophan, other amino acids, and steroid hormones have been implicated in aggression. We compared tryptophan, competing long amino acids (CAAs), and cortisol in serum (S) and CSF in 22 violent offenders and 15 healthy controls. Offenders had significantly increased S-L-tryptophan, S-free tryptophan, S-CAAs, S-cortisol and CSF-cortisol, indicating abnormal neurophysiological processes. Larger studies on the interplay between violence, serotonin precursors, and stress hormones need to integrate personality traits, life situations, and physiological adaptation.},
  author       = {Anckarsäter, Henrik and Blennow, Kaj and Forsman, A and Liesivuori, J and Pennanen, S and Tiihonen, J},
  issn         = {0300-9564},
  keyword      = {Forensic psychiatry,violent behavior,serotonin,cortisol},
  language     = {eng},
  number       = {12},
  pages        = {1605--1610},
  publisher    = {Springer},
  series       = {Journal of Neural Transmission},
  title        = {A controlled study of tryptophan and cortisol in violent offenders},
  url          = {http://dx.doi.org/10.1007/s00702-004-0219-7},
  volume       = {111},
  year         = {2004},
}