Advanced

Elevated triiodothyronine in psychopathy - possible physiological mechanisms

Anckarsäter, Henrik LU and Forsman, A (2004) In Journal of Neural Transmission 111(6). p.739-744
Abstract
We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Thyroid, deiodination, antibodies, aggression, violent offenders, PCL-R psychopathy
in
Journal of Neural Transmission
volume
111
issue
6
pages
739 - 744
publisher
Springer
external identifiers
  • pmid:15168221
  • scopus:2642530535
ISSN
0300-9564
DOI
10.1007/s00702-004-0137-8
language
English
LU publication?
no
id
7243d8e2-439b-4d14-8ec2-f3541a35aba8 (old id 1129393)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/15168221
http://link.springer.com/article/10.1007%2Fs00702-004-0137-8
date added to LUP
2013-10-10 15:00:05
date last changed
2017-01-01 06:45:49
@article{7243d8e2-439b-4d14-8ec2-f3541a35aba8,
  abstract     = {We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17-45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.},
  author       = {Anckarsäter, Henrik and Forsman, A},
  issn         = {0300-9564},
  keyword      = {Thyroid,deiodination,antibodies,aggression,violent offenders,PCL-R psychopathy},
  language     = {eng},
  number       = {6},
  pages        = {739--744},
  publisher    = {Springer},
  series       = {Journal of Neural Transmission},
  title        = {Elevated triiodothyronine in psychopathy - possible physiological mechanisms},
  url          = {http://dx.doi.org/10.1007/s00702-004-0137-8},
  volume       = {111},
  year         = {2004},
}