Insulin allergy and resistance successfully treated by desensitisation with Aspart insulin
(2005) In Clinical and Molecular Allergy 3(16).- Abstract
- A 25-year-old, with type I Diabetes Mellitus with a previous diagnosis of Protamine Allergy but not to human Insulin, started to notice anaphylactic reactions immediately after bolus with Insulin. Skin prick and intradermal test were positive to all insulins. Skin tests to other potential allergens resulted negative. Examination after bolus of Human Insulin revealed urticaria. Daily insulin requirement were around 2-2,4 U/Kg/day. Slow desensitisation with Aspart insulin, the insulin with lowest size of skin test, was performed using subcutaneous insulin pump. Six months after the end of desensitisation his daily insulin requirement decreased to 0.8 U/Kg/day and oral corticosteroids are being reduced with no symptoms.
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https://lup.lub.lu.se/record/1132265
- author
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical and Molecular Allergy
- volume
- 3
- issue
- 16
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:16375762
- scopus:30044435979
- ISSN
- 1476-7961
- DOI
- 10.1186/1476-7961-3-16
- language
- English
- LU publication?
- yes
- id
- b5687512-3f28-49da-87dd-8b5321407430 (old id 1132265)
- date added to LUP
- 2016-04-01 16:59:52
- date last changed
- 2022-04-23 01:59:30
@article{b5687512-3f28-49da-87dd-8b5321407430, abstract = {{A 25-year-old, with type I Diabetes Mellitus with a previous diagnosis of Protamine Allergy but not to human Insulin, started to notice anaphylactic reactions immediately after bolus with Insulin. Skin prick and intradermal test were positive to all insulins. Skin tests to other potential allergens resulted negative. Examination after bolus of Human Insulin revealed urticaria. Daily insulin requirement were around 2-2,4 U/Kg/day. Slow desensitisation with Aspart insulin, the insulin with lowest size of skin test, was performed using subcutaneous insulin pump. Six months after the end of desensitisation his daily insulin requirement decreased to 0.8 U/Kg/day and oral corticosteroids are being reduced with no symptoms.}}, author = {{Matheu, Victor and Perez, Eva and Hernandez, Marta and Diaz, Elisa and Darias, Ricardo and Gonzalez, Abel and Garcia, Jose C and Sanchez, Inmaculada and Feliciano, Laura and Caballero, Agueda and de la Torre, Fernando}}, issn = {{1476-7961}}, language = {{eng}}, number = {{16}}, publisher = {{BioMed Central (BMC)}}, series = {{Clinical and Molecular Allergy}}, title = {{Insulin allergy and resistance successfully treated by desensitisation with Aspart insulin}}, url = {{http://dx.doi.org/10.1186/1476-7961-3-16}}, doi = {{10.1186/1476-7961-3-16}}, volume = {{3}}, year = {{2005}}, }