Activities of daily living - Outcome during two years in galantamine treated Alzheimer patients
(2007) 8th International Conference on Alzheimer`s and Parkinson`s Diseases (AD/PD 2007) p.251-255- Abstract
- 122 patients with Alzheimer's disease receiving galantamine in the Swedish Alzheimer Treatment Study were studied with respect to longitudinal change in cognition (MMSE and ADAS-cog) and function (IADL, PSMS and FAST). Particularly the FAST mean change from baseline showed a linear relationship with cognitive mean change and the strength of the relationship increased over time. The IADL scale demonstrated a faster decline of function, but significantly less than expected by using the mathematical model by Green et al. A cluster analysis was performed to reveal any natural groupings of the patients based on the functional scores at baseline. The two-cluster solution was significant; patients in cluster 1 were more cognitively impaired at... (More)
- 122 patients with Alzheimer's disease receiving galantamine in the Swedish Alzheimer Treatment Study were studied with respect to longitudinal change in cognition (MMSE and ADAS-cog) and function (IADL, PSMS and FAST). Particularly the FAST mean change from baseline showed a linear relationship with cognitive mean change and the strength of the relationship increased over time. The IADL scale demonstrated a faster decline of function, but significantly less than expected by using the mathematical model by Green et al. A cluster analysis was performed to reveal any natural groupings of the patients based on the functional scores at baseline. The two-cluster solution was significant; patients in cluster 1 were more cognitively impaired at baseline, they were less apt to carry the APOE e4 allele and declined faster in the outcome of PSMS score compared to the other group. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1141935
- author
- Wattmo, Carina LU ; Wallin, Åsa LU and Minthon, Lennart LU
- organization
- publishing date
- 2007
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- New Trends in Alzheimer and Parkinson Related Disorders: ADPD 2007
- pages
- 251 - 255
- publisher
- Medimond
- conference name
- 8th International Conference on Alzheimer`s and Parkinson`s Diseases (AD/PD 2007)
- conference location
- Salzburg, Austria
- conference dates
- 2007-03-14 - 2007-03-18
- external identifiers
-
- wos:000257460200036
- ISBN
- 978-88-7587-405-6
- language
- English
- LU publication?
- yes
- additional info
- Poster presentation
- id
- 636285be-fed3-49ac-96d1-39453f8d3a6f (old id 1141935)
- date added to LUP
- 2016-04-04 12:16:33
- date last changed
- 2018-11-21 21:10:01
@inproceedings{636285be-fed3-49ac-96d1-39453f8d3a6f, abstract = {{122 patients with Alzheimer's disease receiving galantamine in the Swedish Alzheimer Treatment Study were studied with respect to longitudinal change in cognition (MMSE and ADAS-cog) and function (IADL, PSMS and FAST). Particularly the FAST mean change from baseline showed a linear relationship with cognitive mean change and the strength of the relationship increased over time. The IADL scale demonstrated a faster decline of function, but significantly less than expected by using the mathematical model by Green et al. A cluster analysis was performed to reveal any natural groupings of the patients based on the functional scores at baseline. The two-cluster solution was significant; patients in cluster 1 were more cognitively impaired at baseline, they were less apt to carry the APOE e4 allele and declined faster in the outcome of PSMS score compared to the other group.}}, author = {{Wattmo, Carina and Wallin, Åsa and Minthon, Lennart}}, booktitle = {{New Trends in Alzheimer and Parkinson Related Disorders: ADPD 2007}}, isbn = {{978-88-7587-405-6}}, language = {{eng}}, pages = {{251--255}}, publisher = {{Medimond}}, title = {{Activities of daily living - Outcome during two years in galantamine treated Alzheimer patients}}, url = {{https://lup.lub.lu.se/search/files/5968106/4175690.pdf}}, year = {{2007}}, }