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Steroid hormone determination in water using an environmentally friendly membrane based extraction technique.

Zorita, Saioa LU ; Hallgren, Pär LU and Mathiasson, Lennart LU (2008) In Journal of Chromatography A 1192(1). p.1-8
Abstract
In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation... (More)
In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation coefficients better than 0.995 and resulted in a method limit of detection of 1.6, 3 and 10ngL(-1) for 17beta-estradiol, estrone, and 17alpha-ethynylestradiol, respectively, in sewage water. Enrichment factors were over 1400 after derivatisation. The repeatabilities at 50 and 600ngL(-1) were better than 10% and 6%, respectively. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Chromatography A
volume
1192
issue
1
pages
1 - 8
publisher
Elsevier
external identifiers
  • wos:000256200700001
  • pmid:18394632
  • scopus:42649129327
ISSN
0021-9673
DOI
10.1016/j.chroma.2008.03.030
language
English
LU publication?
yes
id
5ed0f8f8-f95a-4afe-8c42-0a1e94a97315 (old id 1147657)
date added to LUP
2009-03-09 12:29:00
date last changed
2017-07-30 04:05:12
@article{5ed0f8f8-f95a-4afe-8c42-0a1e94a97315,
  abstract     = {In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation coefficients better than 0.995 and resulted in a method limit of detection of 1.6, 3 and 10ngL(-1) for 17beta-estradiol, estrone, and 17alpha-ethynylestradiol, respectively, in sewage water. Enrichment factors were over 1400 after derivatisation. The repeatabilities at 50 and 600ngL(-1) were better than 10% and 6%, respectively.},
  author       = {Zorita, Saioa and Hallgren, Pär and Mathiasson, Lennart},
  issn         = {0021-9673},
  language     = {eng},
  number       = {1},
  pages        = {1--8},
  publisher    = {Elsevier},
  series       = {Journal of Chromatography A},
  title        = {Steroid hormone determination in water using an environmentally friendly membrane based extraction technique.},
  url          = {http://dx.doi.org/10.1016/j.chroma.2008.03.030},
  volume       = {1192},
  year         = {2008},
}