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Steroid hormone determination in water using an environmentally friendly membrane based extraction technique.

Zorita, Saioa LU ; Hallgren, Pär LU and Mathiasson, Lennart LU (2008) In Journal of Chromatography A 1192(1). p.1-8
Abstract
In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation... (More)
In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation coefficients better than 0.995 and resulted in a method limit of detection of 1.6, 3 and 10ngL(-1) for 17beta-estradiol, estrone, and 17alpha-ethynylestradiol, respectively, in sewage water. Enrichment factors were over 1400 after derivatisation. The repeatabilities at 50 and 600ngL(-1) were better than 10% and 6%, respectively. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Chromatography A
volume
1192
issue
1
pages
1 - 8
publisher
Elsevier
external identifiers
  • wos:000256200700001
  • pmid:18394632
  • scopus:42649129327
  • pmid:18394632
ISSN
0021-9673
DOI
10.1016/j.chroma.2008.03.030
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
id
5ed0f8f8-f95a-4afe-8c42-0a1e94a97315 (old id 1147657)
date added to LUP
2016-04-01 13:36:22
date last changed
2022-01-27 20:04:10
@article{5ed0f8f8-f95a-4afe-8c42-0a1e94a97315,
  abstract     = {{In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic liquid in the lumen (10muL) of the hollow-fibre membrane was utilised for depleting extraction. Several parameters were studied, including: type of organic solvent, sample pH, salt and humic acid content. The optimised method allowed the determination of the analyte at the low ngL(-1) level in tap and sewage water. A linear plot gave correlation coefficients better than 0.995 and resulted in a method limit of detection of 1.6, 3 and 10ngL(-1) for 17beta-estradiol, estrone, and 17alpha-ethynylestradiol, respectively, in sewage water. Enrichment factors were over 1400 after derivatisation. The repeatabilities at 50 and 600ngL(-1) were better than 10% and 6%, respectively.}},
  author       = {{Zorita, Saioa and Hallgren, Pär and Mathiasson, Lennart}},
  issn         = {{0021-9673}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{1--8}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Chromatography A}},
  title        = {{Steroid hormone determination in water using an environmentally friendly membrane based extraction technique.}},
  url          = {{http://dx.doi.org/10.1016/j.chroma.2008.03.030}},
  doi          = {{10.1016/j.chroma.2008.03.030}},
  volume       = {{1192}},
  year         = {{2008}},
}