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Assessment of autonomic symptoms in diabetics: the Swedish version of the Autonomic Symptom Profile.

Mandl, Thomas LU ; Granberg, Viktoria LU ; Apelqvist, Jan LU ; Wollmer, Per LU ; Manthorpe, Rolf LU and Jacobsson, Lennart LU (2008) In Clinical Physiology and Functional Imaging 28. p.312-317
Abstract
Objectives: Autonomic dysfunction (AD) is a complication of diabetes and may be associated with troubling symptoms and increased mortality. Commonly, AD is detected by objective physiological tests and only recently, a validated self-completed English questionnaire assessing AD symptoms, the Autonomic Symptom Profile (ASP), was developed. The aims of this study were to translate the ASP into Swedish and evaluate its reliability and validity. Methods: Forward and back translations were performed. Thirty-one patients with type I diabetes, 200 population-based controls and two AD experts participated in the study. Test-retest reliability was evaluated by letting 25 patients to fill in the ASP twice. Content validity was evaluated by two... (More)
Objectives: Autonomic dysfunction (AD) is a complication of diabetes and may be associated with troubling symptoms and increased mortality. Commonly, AD is detected by objective physiological tests and only recently, a validated self-completed English questionnaire assessing AD symptoms, the Autonomic Symptom Profile (ASP), was developed. The aims of this study were to translate the ASP into Swedish and evaluate its reliability and validity. Methods: Forward and back translations were performed. Thirty-one patients with type I diabetes, 200 population-based controls and two AD experts participated in the study. Test-retest reliability was evaluated by letting 25 patients to fill in the ASP twice. Content validity was evaluated by two Swedish AD experts and construct validity was evaluated by studying associations between the ASP total score and five objective autonomic nervous function test variables. Finally, discriminant validity was evaluated by studying differences in the ASP total and domain scores between patients and controls. Results: The translation was accepted without changes. Test-retest reliability and content validity of the Swedish ASP were considered good. The construct validity was considered acceptable with two significant associations between the ASP total score and the autonomic nervous function test variables. In addition, discriminant validity was considered acceptable with regard to the ASP total score as well as the sexual dysfunction, sleep disorder and vasomotor dysfunction domain scores significantly differing between patients and controls. Conclusion: The Swedish version of the ASP was considered a reliable and valid instrument for the study of AD symptoms in patients with type I diabetes. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging
volume
28
pages
312 - 317
publisher
Wiley Online Library
external identifiers
  • wos:000258376700006
  • pmid:18462437
  • scopus:49849093800
ISSN
1475-0961
DOI
10.1111/j.1475-097X.2008.00810.x
language
English
LU publication?
yes
id
8926c2ae-85cb-45e8-9d66-bedd325e864a (old id 1154472)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18462437?dopt=Abstract
date added to LUP
2008-06-02 12:44:55
date last changed
2017-01-01 07:37:29
@article{8926c2ae-85cb-45e8-9d66-bedd325e864a,
  abstract     = {Objectives: Autonomic dysfunction (AD) is a complication of diabetes and may be associated with troubling symptoms and increased mortality. Commonly, AD is detected by objective physiological tests and only recently, a validated self-completed English questionnaire assessing AD symptoms, the Autonomic Symptom Profile (ASP), was developed. The aims of this study were to translate the ASP into Swedish and evaluate its reliability and validity. Methods: Forward and back translations were performed. Thirty-one patients with type I diabetes, 200 population-based controls and two AD experts participated in the study. Test-retest reliability was evaluated by letting 25 patients to fill in the ASP twice. Content validity was evaluated by two Swedish AD experts and construct validity was evaluated by studying associations between the ASP total score and five objective autonomic nervous function test variables. Finally, discriminant validity was evaluated by studying differences in the ASP total and domain scores between patients and controls. Results: The translation was accepted without changes. Test-retest reliability and content validity of the Swedish ASP were considered good. The construct validity was considered acceptable with two significant associations between the ASP total score and the autonomic nervous function test variables. In addition, discriminant validity was considered acceptable with regard to the ASP total score as well as the sexual dysfunction, sleep disorder and vasomotor dysfunction domain scores significantly differing between patients and controls. Conclusion: The Swedish version of the ASP was considered a reliable and valid instrument for the study of AD symptoms in patients with type I diabetes.},
  author       = {Mandl, Thomas and Granberg, Viktoria and Apelqvist, Jan and Wollmer, Per and Manthorpe, Rolf and Jacobsson, Lennart},
  issn         = {1475-0961},
  language     = {eng},
  pages        = {312--317},
  publisher    = {Wiley Online Library},
  series       = {Clinical Physiology and Functional Imaging},
  title        = {Assessment of autonomic symptoms in diabetics: the Swedish version of the Autonomic Symptom Profile.},
  url          = {http://dx.doi.org/10.1111/j.1475-097X.2008.00810.x},
  volume       = {28},
  year         = {2008},
}