Lower breast cancer survival in mothers of children with a malignancy: a national study.
Olsson, Håkan LU
; Magnusson, Susanne
LU
and Bladström, Anna
LU
(2008)
In British Journal of Cancer
98(11).
p.1876-1878
- Abstract
- As it is unclear if hereditary factors affect breast cancer survival, this was compared using fertility and cancer registry data, among all women so diagnosed during 1961-1999 in Sweden, having a child with childhood cancer (<or=20 years of age; n=254) and with that of other women (n=74,781). Those having a child with a childhood malignancy had a significantly worse survival than other women, relative risk (RR)=1.25, 95% CI 1.02-1.55, P<0.04, adjusted for age at diagnosis, year of diagnosis, parity and time since last pregnancy. Childhood sarcomas or acute myeloid leukaemia seemed to be most associated with a worse survival in the mother (RR=1.38 and 1.69, respectively). The lower survival of the mother was present for breast cancer... (More)
- As it is unclear if hereditary factors affect breast cancer survival, this was compared using fertility and cancer registry data, among all women so diagnosed during 1961-1999 in Sweden, having a child with childhood cancer (<or=20 years of age; n=254) and with that of other women (n=74,781). Those having a child with a childhood malignancy had a significantly worse survival than other women, relative risk (RR)=1.25, 95% CI 1.02-1.55, P<0.04, adjusted for age at diagnosis, year of diagnosis, parity and time since last pregnancy. Childhood sarcomas or acute myeloid leukaemia seemed to be most associated with a worse survival in the mother (RR=1.38 and 1.69, respectively). The lower survival of the mother was present for breast cancer diagnosed both before and after 50 years of age. The Li-Fraumeni syndrome and possibly other genetic disorders may lower breast cancer survival. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1154547
- author
- Olsson, Håkan
LU
; Magnusson, Susanne
LU
and Bladström, Anna
LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Cancer
- volume
- 98
- issue
- 11
- pages
- 1876 - 1878
- publisher
- Nature Publishing Group
- external identifiers
-
- wos:000256308600026
- pmid:18458676
- scopus:44349107014
- ISSN
- 1532-1827
- DOI
- 10.1038/sj.bjc.6604350
- language
- English
- LU publication?
- yes
- id
- 28ef7775-876d-42ad-973a-5ef7305c028f (old id 1154547)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18458676?dopt=Abstract
- date added to LUP
- 2016-04-04 08:55:44
- date last changed
- 2022-01-29 07:45:06
@article{28ef7775-876d-42ad-973a-5ef7305c028f,
abstract = {{As it is unclear if hereditary factors affect breast cancer survival, this was compared using fertility and cancer registry data, among all women so diagnosed during 1961-1999 in Sweden, having a child with childhood cancer (<or=20 years of age; n=254) and with that of other women (n=74,781). Those having a child with a childhood malignancy had a significantly worse survival than other women, relative risk (RR)=1.25, 95% CI 1.02-1.55, P<0.04, adjusted for age at diagnosis, year of diagnosis, parity and time since last pregnancy. Childhood sarcomas or acute myeloid leukaemia seemed to be most associated with a worse survival in the mother (RR=1.38 and 1.69, respectively). The lower survival of the mother was present for breast cancer diagnosed both before and after 50 years of age. The Li-Fraumeni syndrome and possibly other genetic disorders may lower breast cancer survival.}},
author = {{Olsson, Håkan and Magnusson, Susanne and Bladström, Anna}},
issn = {{1532-1827}},
language = {{eng}},
number = {{11}},
pages = {{1876--1878}},
publisher = {{Nature Publishing Group}},
series = {{British Journal of Cancer}},
title = {{Lower breast cancer survival in mothers of children with a malignancy: a national study.}},
url = {{http://dx.doi.org/10.1038/sj.bjc.6604350}},
doi = {{10.1038/sj.bjc.6604350}},
volume = {{98}},
year = {{2008}},
}