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Utilisation of antibiotics in young children: opposite relationships to adult educational levels in Danish and Swedish counties.

Melander, Eva; Nissen, Aase; Henricson, Karin LU ; Merlo, Juan LU ; Mölstad, Sigvard; Kampmann, Jens P.; Lithman, Thor; Hansen, Ebba Holme and Melander, Arne LU (2003) In European Journal of Clinical Pharmacology 59(4). p.331-335
Abstract
Background. Antibiotic utilisation varies profoundly among and within countries, and the extent of antibiotic utilisation correlates with the frequency of bacterial resistance, particularly among children. Hence, it is important to assess which factors may influence prescribing. In addition to variations in morbidity, health-care organisation, drug regulatory and supply systems, prescriber's attitudes, parents' behaviour, attitudes and socio-economic positions seem important. We compared socio-economic position (educational level of adults) and antibiotic utilisation in children in the municipalities within a Danish and a Swedish county which are geographically close, have similar social and economic development, and similar drug... (More)
Background. Antibiotic utilisation varies profoundly among and within countries, and the extent of antibiotic utilisation correlates with the frequency of bacterial resistance, particularly among children. Hence, it is important to assess which factors may influence prescribing. In addition to variations in morbidity, health-care organisation, drug regulatory and supply systems, prescriber's attitudes, parents' behaviour, attitudes and socio-economic positions seem important. We compared socio-economic position (educational level of adults) and antibiotic utilisation in children in the municipalities within a Danish and a Swedish county which are geographically close, have similar social and economic development, and similar drug regulatory and supply systems. Methods. Data on antibiotic utilisation (1998), expressed in defined daily doses per 1000 inhabitants per day (DDD/TID), were obtained from the Copenhagen County Health Insurance register and from the National Corporation of Swedish Pharmacies. Data on municipal educational levels were obtained from Statistics Denmark and Statistics Sweden. Results. The utilisation of antibiotics in 0- to 6-year-old children was higher in the Swedish than in the Danish county but varied between the municipalities within both the Swedish (9.6-17.7 DDD/TID) and the Danish (8.0-12.9 DDD/TID) counties. Most notably, utilisation rates correlated negatively with the education levels in the Danish (r=-0.539, P=0.021) but positively in the Swedish (r=+0.390, P=0.025) municipalities. Conclusion. The observed variations in antibiotic prescribing may reflect different parental and/or prescriber attitudes towards use of antibiotics and they emphasise that antibiotic prescribing is influenced by factors other than the prevalence of bacterial infections. Relationships between socio-economic position (educational level) and drug utilisation should not be generalised from one area to another. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
children, utilisation, antibiotics
in
European Journal of Clinical Pharmacology
volume
59
issue
4
pages
331 - 335
publisher
Springer
external identifiers
  • wos:000184777200010
  • pmid:12856093
  • scopus:0042913336
ISSN
1432-1041
DOI
10.1007/s00228-003-0624-0
language
English
LU publication?
yes
id
9792d755-1cf3-4680-9ea0-efa5f2668951 (old id 116490)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12856093&dopt=Abstract
date added to LUP
2007-07-26 13:04:30
date last changed
2017-01-01 07:06:42
@article{9792d755-1cf3-4680-9ea0-efa5f2668951,
  abstract     = {Background. Antibiotic utilisation varies profoundly among and within countries, and the extent of antibiotic utilisation correlates with the frequency of bacterial resistance, particularly among children. Hence, it is important to assess which factors may influence prescribing. In addition to variations in morbidity, health-care organisation, drug regulatory and supply systems, prescriber's attitudes, parents' behaviour, attitudes and socio-economic positions seem important. We compared socio-economic position (educational level of adults) and antibiotic utilisation in children in the municipalities within a Danish and a Swedish county which are geographically close, have similar social and economic development, and similar drug regulatory and supply systems. Methods. Data on antibiotic utilisation (1998), expressed in defined daily doses per 1000 inhabitants per day (DDD/TID), were obtained from the Copenhagen County Health Insurance register and from the National Corporation of Swedish Pharmacies. Data on municipal educational levels were obtained from Statistics Denmark and Statistics Sweden. Results. The utilisation of antibiotics in 0- to 6-year-old children was higher in the Swedish than in the Danish county but varied between the municipalities within both the Swedish (9.6-17.7 DDD/TID) and the Danish (8.0-12.9 DDD/TID) counties. Most notably, utilisation rates correlated negatively with the education levels in the Danish (r=-0.539, P=0.021) but positively in the Swedish (r=+0.390, P=0.025) municipalities. Conclusion. The observed variations in antibiotic prescribing may reflect different parental and/or prescriber attitudes towards use of antibiotics and they emphasise that antibiotic prescribing is influenced by factors other than the prevalence of bacterial infections. Relationships between socio-economic position (educational level) and drug utilisation should not be generalised from one area to another.},
  author       = {Melander, Eva and Nissen, Aase and Henricson, Karin and Merlo, Juan and Mölstad, Sigvard and Kampmann, Jens P. and Lithman, Thor and Hansen, Ebba Holme and Melander, Arne},
  issn         = {1432-1041},
  keyword      = {children,utilisation,antibiotics},
  language     = {eng},
  number       = {4},
  pages        = {331--335},
  publisher    = {Springer},
  series       = {European Journal of Clinical Pharmacology},
  title        = {Utilisation of antibiotics in young children: opposite relationships to adult educational levels in Danish and Swedish counties.},
  url          = {http://dx.doi.org/10.1007/s00228-003-0624-0},
  volume       = {59},
  year         = {2003},
}