The role of CT-assessed sarcopenia and visceral adipose tissue in predicting long-term survival in patients undergoing elective endovascular infrarenal aortic repair
(2024) In The British journal of radiology 97(1160). p.1461-1466- Abstract
OBJECTIVES: To evaluate if ileo-psoas muscle size and visceral adipose tissue (VAT) can predict long-term survival after endovascular aneurysm repair (EVAR). METHODS: Patients who underwent EVAR between 2004 and 2012 in a single centre were included. Total psoas muscle area (TPA), abdominal VAT area, subcutaneous adipose tissue (SAT), and total adipose tissue were measured on the preoperative CT. Primary endpoint was all-cause mortality. Values are presented as median and interquartile range or absolute number and percentage. Cox regression analyses were performed to assess the associations with mortality. RESULTS: Two hundred and eighty-four patients could be included in the study. During a median follow-up of 8 (4-11) years, 223... (More)
OBJECTIVES: To evaluate if ileo-psoas muscle size and visceral adipose tissue (VAT) can predict long-term survival after endovascular aneurysm repair (EVAR). METHODS: Patients who underwent EVAR between 2004 and 2012 in a single centre were included. Total psoas muscle area (TPA), abdominal VAT area, subcutaneous adipose tissue (SAT), and total adipose tissue were measured on the preoperative CT. Primary endpoint was all-cause mortality. Values are presented as median and interquartile range or absolute number and percentage. Cox regression analyses were performed to assess the associations with mortality. RESULTS: Two hundred and eighty-four patients could be included in the study. During a median follow-up of 8 (4-11) years, 223 (79.9%) patients died. Age (P ≤ .001), cardiovascular (P = .041), cerebrovascular (P = .009), renal diseases (P = .002), and chronic obstructive pulmonary disease (P ≤ .001) were independently associated with mortality. TPA was associated with mortality in a univariate (P = .040), but not in a multivariate regression model (P = .764). No significant association was found between mortality and TPA index (P = .103) or any of the adiposity measurements with the exception of SAT (P = .040). However, SAT area loss in a multivariate analysis (P = .875). CONCLUSIONS: Assessment of core muscle size and VAT did not contribute to improving the prediction of long-term survival after EVAR. ADVANCES IN KNOWLEDGE: The finding of this study contradicts the previously claimed utility of core muscle size and VAT in predicting long-term survival after EVAR.
(Less)
- author
- Vaccarino, Roberta
LU
; Wachtmeister, Melker
; Karelis, Angelos
LU
; Marinko, Elisabet LU ; Sun, Jianming ; Resch, Timothy LU ; Sonesson, Björn LU and Dias, Nuno V. LU
- organization
- publishing date
- 2024-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- EVAR, ileo-psoas muscle size, preoperative risk assessment, visceral adipose tissue
- in
- The British journal of radiology
- volume
- 97
- issue
- 1160
- pages
- 6 pages
- publisher
- British Institute of Radiology
- external identifiers
-
- pmid:38848475
- scopus:85199224235
- ISSN
- 1748-880X
- DOI
- 10.1093/bjr/tqae114
- language
- English
- LU publication?
- yes
- id
- 116ded4c-8ed0-4e21-a7e9-96e8659c8a8e
- date added to LUP
- 2024-09-09 15:34:28
- date last changed
- 2024-09-10 03:11:35
@article{116ded4c-8ed0-4e21-a7e9-96e8659c8a8e, abstract = {{<p>OBJECTIVES: To evaluate if ileo-psoas muscle size and visceral adipose tissue (VAT) can predict long-term survival after endovascular aneurysm repair (EVAR). METHODS: Patients who underwent EVAR between 2004 and 2012 in a single centre were included. Total psoas muscle area (TPA), abdominal VAT area, subcutaneous adipose tissue (SAT), and total adipose tissue were measured on the preoperative CT. Primary endpoint was all-cause mortality. Values are presented as median and interquartile range or absolute number and percentage. Cox regression analyses were performed to assess the associations with mortality. RESULTS: Two hundred and eighty-four patients could be included in the study. During a median follow-up of 8 (4-11) years, 223 (79.9%) patients died. Age (P ≤ .001), cardiovascular (P = .041), cerebrovascular (P = .009), renal diseases (P = .002), and chronic obstructive pulmonary disease (P ≤ .001) were independently associated with mortality. TPA was associated with mortality in a univariate (P = .040), but not in a multivariate regression model (P = .764). No significant association was found between mortality and TPA index (P = .103) or any of the adiposity measurements with the exception of SAT (P = .040). However, SAT area loss in a multivariate analysis (P = .875). CONCLUSIONS: Assessment of core muscle size and VAT did not contribute to improving the prediction of long-term survival after EVAR. ADVANCES IN KNOWLEDGE: The finding of this study contradicts the previously claimed utility of core muscle size and VAT in predicting long-term survival after EVAR.</p>}}, author = {{Vaccarino, Roberta and Wachtmeister, Melker and Karelis, Angelos and Marinko, Elisabet and Sun, Jianming and Resch, Timothy and Sonesson, Björn and Dias, Nuno V.}}, issn = {{1748-880X}}, keywords = {{EVAR; ileo-psoas muscle size; preoperative risk assessment; visceral adipose tissue}}, language = {{eng}}, number = {{1160}}, pages = {{1461--1466}}, publisher = {{British Institute of Radiology}}, series = {{The British journal of radiology}}, title = {{The role of CT-assessed sarcopenia and visceral adipose tissue in predicting long-term survival in patients undergoing elective endovascular infrarenal aortic repair}}, url = {{http://dx.doi.org/10.1093/bjr/tqae114}}, doi = {{10.1093/bjr/tqae114}}, volume = {{97}}, year = {{2024}}, }