Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.
(2008) In Langenbeck's Archives of Surgery 393. p.667-673- Abstract
- BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was... (More)
- BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months. CONCLUSION: Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1181088
- author
- Bergenfelz, Anders LU ; Jansson, S ; Kristoffersson, Ann-Charlotte LU ; Mårtensson, H ; Reihnér, E ; Wallin, G and Lausen, I
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Langenbeck's Archives of Surgery
- volume
- 393
- pages
- 667 - 673
- publisher
- Springer
- external identifiers
-
- wos:000259007800009
- pmid:18633639
- scopus:51449087796
- ISSN
- 1435-2451
- DOI
- 10.1007/s00423-008-0366-7
- language
- English
- LU publication?
- yes
- id
- b766de57-e0f6-4a1c-af4d-5b68e8abd9b3 (old id 1181088)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18633639?dopt=Abstract
- date added to LUP
- 2016-04-04 09:19:27
- date last changed
- 2022-04-15 22:43:47
@article{b766de57-e0f6-4a1c-af4d-5b68e8abd9b3, abstract = {{BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months. CONCLUSION: Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern.}}, author = {{Bergenfelz, Anders and Jansson, S and Kristoffersson, Ann-Charlotte and Mårtensson, H and Reihnér, E and Wallin, G and Lausen, I}}, issn = {{1435-2451}}, language = {{eng}}, pages = {{667--673}}, publisher = {{Springer}}, series = {{Langenbeck's Archives of Surgery}}, title = {{Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.}}, url = {{http://dx.doi.org/10.1007/s00423-008-0366-7}}, doi = {{10.1007/s00423-008-0366-7}}, volume = {{393}}, year = {{2008}}, }