Acoustophoresis in wet-etched glass chips
Evander, Mikael LU ; Lenshof, Andreas LU
; Laurell, Thomas
LU
and Nilsson, Johan
LU
(2008)
In Analytical Chemistry
80(13).
p.5178-5185
- Abstract
- Acoustophoresis in microfluidic structures has primarily been reported in silicon microfabricated devices. This paper demonstrates, for the first time, acoustophoresis performed in isotropically etched glass chips providing a performance that matches that of the corresponding silicon microdevices. The resonance mode characteristics of the glass chip were equal to those of the silicon chip at its fundamental resonance. At higher order resonance modes the glass chip displays resonances at lower frequencies than the silicon chip. The cross-sectional profiles of acoustically focused particle streams are also reported for the first time, displaying particles confined in a vertical band in the channel center for both glass and silicon chips. A... (More)
- Acoustophoresis in microfluidic structures has primarily been reported in silicon microfabricated devices. This paper demonstrates, for the first time, acoustophoresis performed in isotropically etched glass chips providing a performance that matches that of the corresponding silicon microdevices. The resonance mode characteristics of the glass chip were equal to those of the silicon chip at its fundamental resonance. At higher order resonance modes the glass chip displays resonances at lower frequencies than the silicon chip. The cross-sectional profiles of acoustically focused particle streams are also reported for the first time, displaying particles confined in a vertical band in the channel center for both glass and silicon chips. A particle extraction efficiency of 98% at flow rates up to 200 mu L/min (2% particle concentration) is reported for the glass chip at the fundamental resonance. The glass and silicon chips displayed equal particle extraction performance when tested for increasing particle concentrations of 2-15%, at a flow velocity of 12.9 cm/s for the glass chip and 14.8 cm/s for the silicon chip. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1187189
- author
- Evander, Mikael
LU
; Lenshof, Andreas
LU
; Laurell, Thomas
LU
and Nilsson, Johan
LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Analytical Chemistry
- volume
- 80
- issue
- 13
- pages
- 5178 - 5185
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000257270600055
- scopus:46849105643
- ISSN
- 1520-6882
- DOI
- 10.1021/ac800572n
- language
- English
- LU publication?
- yes
- id
- 1ed777ba-87bf-4e3e-8e3c-8d05c1cccd28 (old id 1187189)
- date added to LUP
- 2016-04-01 12:06:32
- date last changed
- 2024-10-08 22:00:50
@article{1ed777ba-87bf-4e3e-8e3c-8d05c1cccd28,
abstract = {{Acoustophoresis in microfluidic structures has primarily been reported in silicon microfabricated devices. This paper demonstrates, for the first time, acoustophoresis performed in isotropically etched glass chips providing a performance that matches that of the corresponding silicon microdevices. The resonance mode characteristics of the glass chip were equal to those of the silicon chip at its fundamental resonance. At higher order resonance modes the glass chip displays resonances at lower frequencies than the silicon chip. The cross-sectional profiles of acoustically focused particle streams are also reported for the first time, displaying particles confined in a vertical band in the channel center for both glass and silicon chips. A particle extraction efficiency of 98% at flow rates up to 200 mu L/min (2% particle concentration) is reported for the glass chip at the fundamental resonance. The glass and silicon chips displayed equal particle extraction performance when tested for increasing particle concentrations of 2-15%, at a flow velocity of 12.9 cm/s for the glass chip and 14.8 cm/s for the silicon chip.}},
author = {{Evander, Mikael and Lenshof, Andreas and Laurell, Thomas and Nilsson, Johan}},
issn = {{1520-6882}},
language = {{eng}},
number = {{13}},
pages = {{5178--5185}},
publisher = {{The American Chemical Society (ACS)}},
series = {{Analytical Chemistry}},
title = {{Acoustophoresis in wet-etched glass chips}},
url = {{http://dx.doi.org/10.1021/ac800572n}},
doi = {{10.1021/ac800572n}},
volume = {{80}},
year = {{2008}},
}