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Long-term cost and effect on quality of life of osteoporosis-related fractures in Sweden

Strom, Oskar; Borgstrom, Fredrik; Zethraeus, Niklas; Johnell, Olof LU ; Lidgren, Lars LU ; Ponzer, Sari; Svensson, Olle; Abdon, Peter; Ornstein, Ewald and Ceder, Leif, et al. (2008) In Acta Orthopaedica 79(2). p.269-280
Abstract
Background and purpose Few economic or quality-of-life studies have investigated the long-term consequences of fragility fractures. This prospective observational data collection study assessed the cost and quality of life related to hip, vertebral, and wrist fracture 13-18 months after the fracture, based on 684 patients surviving 18 months after fracture. Patients and methods Data regarding resource use and quality of life related to fractures was collected using questionnaires at 7 research centers in Sweden. Information was collected using patient records, register sources, and by asking the patient. Quality of life was estimated using the EQ-5D questionnaire. Direct and indirect costs were estimated from a societal standpoint. Results... (More)
Background and purpose Few economic or quality-of-life studies have investigated the long-term consequences of fragility fractures. This prospective observational data collection study assessed the cost and quality of life related to hip, vertebral, and wrist fracture 13-18 months after the fracture, based on 684 patients surviving 18 months after fracture. Patients and methods Data regarding resource use and quality of life related to fractures was collected using questionnaires at 7 research centers in Sweden. Information was collected using patient records, register sources, and by asking the patient. Quality of life was estimated using the EQ-5D questionnaire. Direct and indirect costs were estimated from a societal standpoint. Results The mean fracture-related cost 13-18 months after a hip, vertebral, or wrist fracture were estimated to be (sic)2,422, (sic)3,628, and (sic)316, respectively. Between 12 and 18 months after hip, vertebral, and wrist fracture, utility increased by 0.03, 0.05, and 0.02, respectively. Compared to prefracture levels, the mean loss in quality of life between 13 and 18 months after fracture was estimated to be 0.05, 0.11, and 0.005 for hip, vertebral, and wrist fracture. Interpretation The sample of vertebral fracture patients was fairly small and included a high proportion of fractures leading to hospitalization, but the results indicate higher long-term costs and greater loss in quality of life related to vertebral fracture than previously believed. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
volume
79
issue
2
pages
269 - 280
publisher
Taylor & Francis
external identifiers
  • wos:000256188900017
  • scopus:44249116046
ISSN
1745-3682
DOI
10.1080/17453670710015094
language
English
LU publication?
yes
id
25e5993a-7696-4824-b2cf-436263b4bf3d (old id 1201912)
date added to LUP
2008-09-15 12:58:00
date last changed
2017-10-29 04:02:58
@article{25e5993a-7696-4824-b2cf-436263b4bf3d,
  abstract     = {Background and purpose Few economic or quality-of-life studies have investigated the long-term consequences of fragility fractures. This prospective observational data collection study assessed the cost and quality of life related to hip, vertebral, and wrist fracture 13-18 months after the fracture, based on 684 patients surviving 18 months after fracture. Patients and methods Data regarding resource use and quality of life related to fractures was collected using questionnaires at 7 research centers in Sweden. Information was collected using patient records, register sources, and by asking the patient. Quality of life was estimated using the EQ-5D questionnaire. Direct and indirect costs were estimated from a societal standpoint. Results The mean fracture-related cost 13-18 months after a hip, vertebral, or wrist fracture were estimated to be (sic)2,422, (sic)3,628, and (sic)316, respectively. Between 12 and 18 months after hip, vertebral, and wrist fracture, utility increased by 0.03, 0.05, and 0.02, respectively. Compared to prefracture levels, the mean loss in quality of life between 13 and 18 months after fracture was estimated to be 0.05, 0.11, and 0.005 for hip, vertebral, and wrist fracture. Interpretation The sample of vertebral fracture patients was fairly small and included a high proportion of fractures leading to hospitalization, but the results indicate higher long-term costs and greater loss in quality of life related to vertebral fracture than previously believed.},
  author       = {Strom, Oskar and Borgstrom, Fredrik and Zethraeus, Niklas and Johnell, Olof and Lidgren, Lars and Ponzer, Sari and Svensson, Olle and Abdon, Peter and Ornstein, Ewald and Ceder, Leif and Thorngren, Karl Goran and Sernbo, Ingemar and Jönsson, Bengt},
  issn         = {1745-3682},
  language     = {eng},
  number       = {2},
  pages        = {269--280},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica},
  title        = {Long-term cost and effect on quality of life of osteoporosis-related fractures in Sweden},
  url          = {http://dx.doi.org/10.1080/17453670710015094},
  volume       = {79},
  year         = {2008},
}