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Why do chest compressions aid delayed defibrillation?

Chambertain, Douglas; Frenneaux, Michael; Steen, Stig LU and Smith, Andrew (2008) In Resuscitation 77(1). p.10-15
Abstract
The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. In this paper we argue that the concept is inadequate to explain many experimental and clinical. observations made during resuscitation attempts. We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of... (More)
The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. In this paper we argue that the concept is inadequate to explain many experimental and clinical. observations made during resuscitation attempts. We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of the current guidelines of the European Resuscitation Council that we believe to be inconsistent with the evidence that we review. (C) 2007 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ventricular interaction, pathophysiology, cardiac arrest compressions, defibrittation, coronary perfusion pressure, guidelines
in
Resuscitation
volume
77
issue
1
pages
10 - 15
publisher
Elsevier
external identifiers
  • wos:000254678000004
  • scopus:39949083568
ISSN
1873-1570
DOI
10.1016/j.resuscitation.2007.11.010
language
English
LU publication?
yes
id
148b4ea7-8754-458d-9086-2810c30c4748 (old id 1207371)
date added to LUP
2008-08-28 12:44:09
date last changed
2017-01-01 04:31:12
@misc{148b4ea7-8754-458d-9086-2810c30c4748,
  abstract     = {The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. In this paper we argue that the concept is inadequate to explain many experimental and clinical. observations made during resuscitation attempts. We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of the current guidelines of the European Resuscitation Council that we believe to be inconsistent with the evidence that we review. (C) 2007 Elsevier Ireland Ltd. All rights reserved.},
  author       = {Chambertain, Douglas and Frenneaux, Michael and Steen, Stig and Smith, Andrew},
  issn         = {1873-1570},
  keyword      = {ventricular interaction,pathophysiology,cardiac arrest compressions,defibrittation,coronary perfusion pressure,guidelines},
  language     = {eng},
  number       = {1},
  pages        = {10--15},
  publisher    = {Elsevier},
  series       = {Resuscitation},
  title        = {Why do chest compressions aid delayed defibrillation?},
  url          = {http://dx.doi.org/10.1016/j.resuscitation.2007.11.010},
  volume       = {77},
  year         = {2008},
}