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Overactive bladder: prevalence, risk factors and relation to stress incontinence in middle-aged women.

Teleman, Pia LU ; Lidfeldt, Jonas LU ; Nerbrand, Christina LU ; Samsioe, Göran LU and Mattiasson, Anders LU (2004) In BJOG: An International Journal of Obstetrics & Gynaecology2000-01-01+01:00 111(6). p.600-604
Abstract
Objective To investigate the prevalence of and factors associated with overactive bladder in middle-aged women.



Design Cross sectional population-based study.



Setting Southern Sweden and the Women's Health in the Lund Area study (WHILA 1995-2000) where 6917 (64% of the invited) women, 50-59 years old in 1995, participated.



Population From the WHILA study, 1500 women reporting troublesome urinary incontinence (INCONT-1) and 1500 without incontinence (CONT-1) were selected by computerised randomisation and received the Bristol Female Lower Urinary Tract Symptoms (BFLUTS) questionnaire in January 2001.



Methods Overactive bladder was defined in two versions using the... (More)
Objective To investigate the prevalence of and factors associated with overactive bladder in middle-aged women.



Design Cross sectional population-based study.



Setting Southern Sweden and the Women's Health in the Lund Area study (WHILA 1995-2000) where 6917 (64% of the invited) women, 50-59 years old in 1995, participated.



Population From the WHILA study, 1500 women reporting troublesome urinary incontinence (INCONT-1) and 1500 without incontinence (CONT-1) were selected by computerised randomisation and received the Bristol Female Lower Urinary Tract Symptoms (BFLUTS) questionnaire in January 2001.



Methods Overactive bladder was defined in two versions using the ICS definition of 2002 as either urgency alone (OAB-1) or urgency combined with frequency more than eight times per day and/or nocturia twice or more per night (OAB-2). Risk factors were analysed by multiple logistic regression analyses.



Main outcome measures Prevalence figures and odds ratios with corresponding 95% confidence intervals.



Results The prevalence of OAB-1 was 46.9% in the INCONT-1 and 16.7% in the CONT-1 group, and that of OAB-2 was 21.6% and 8.1%, respectively. Most urgency occurred in combination with stress incontinence (i.e. as mixed incontinence). The overlap between stress and urge symptoms increased with the frequency of stress incontinence episodes (P< 0.001). Metabolic risk factors were body mass index (BMI) >= 30 for OAB-1, OAB-2 and stress incontinence, positive metabolic screening for OAB-1, family history of diabetes for OAB-2 and elevation of BMI >= 25% since the age of 25 for stress incontinence. Stress incontinence was associated with the current use of hormonal replacement therapy.



Conclusions Overactive bladder and stress incontinence are intimately associated with each other. Both OAB and stress incontinence are associated with abnormal metabolic factors, mainly increased BMI. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
keywords
Female, Bladder Diseases: epidemiology, Body Mass Index, Chi-Square Distribution, Cross-Sectional Studies, Human, Middle Aged, Odds Ratio, Prevalence, Risk Factors, Urinary Incontinence, Stress: epidemiology
in
BJOG: An International Journal of Obstetrics & Gynaecology2000-01-01+01:00
volume
111
issue
6
pages
600 - 604
publisher
Wiley-Blackwell
external identifiers
  • wos:000221864300015
  • pmid:15198789
  • scopus:2942604198
ISSN
1471-0528
DOI
10.1111/j.1471-0528.2004.00137.x
language
English
LU publication?
yes
id
a1b75163-ac79-40a5-998c-53fd7e64c21a (old id 124141)
alternative location
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15198789&ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
date added to LUP
2007-06-29 16:27:40
date last changed
2017-08-27 05:24:15
@article{a1b75163-ac79-40a5-998c-53fd7e64c21a,
  abstract     = {Objective To investigate the prevalence of and factors associated with overactive bladder in middle-aged women.<br/><br>
<br/><br>
Design Cross sectional population-based study.<br/><br>
<br/><br>
Setting Southern Sweden and the Women's Health in the Lund Area study (WHILA 1995-2000) where 6917 (64% of the invited) women, 50-59 years old in 1995, participated.<br/><br>
<br/><br>
Population From the WHILA study, 1500 women reporting troublesome urinary incontinence (INCONT-1) and 1500 without incontinence (CONT-1) were selected by computerised randomisation and received the Bristol Female Lower Urinary Tract Symptoms (BFLUTS) questionnaire in January 2001.<br/><br>
<br/><br>
Methods Overactive bladder was defined in two versions using the ICS definition of 2002 as either urgency alone (OAB-1) or urgency combined with frequency more than eight times per day and/or nocturia twice or more per night (OAB-2). Risk factors were analysed by multiple logistic regression analyses.<br/><br>
<br/><br>
Main outcome measures Prevalence figures and odds ratios with corresponding 95% confidence intervals.<br/><br>
<br/><br>
Results The prevalence of OAB-1 was 46.9% in the INCONT-1 and 16.7% in the CONT-1 group, and that of OAB-2 was 21.6% and 8.1%, respectively. Most urgency occurred in combination with stress incontinence (i.e. as mixed incontinence). The overlap between stress and urge symptoms increased with the frequency of stress incontinence episodes (P&lt; 0.001). Metabolic risk factors were body mass index (BMI) &gt;= 30 for OAB-1, OAB-2 and stress incontinence, positive metabolic screening for OAB-1, family history of diabetes for OAB-2 and elevation of BMI &gt;= 25% since the age of 25 for stress incontinence. Stress incontinence was associated with the current use of hormonal replacement therapy.<br/><br>
<br/><br>
Conclusions Overactive bladder and stress incontinence are intimately associated with each other. Both OAB and stress incontinence are associated with abnormal metabolic factors, mainly increased BMI.},
  author       = {Teleman, Pia and Lidfeldt, Jonas and Nerbrand, Christina and Samsioe, Göran and Mattiasson, Anders},
  issn         = {1471-0528},
  keyword      = {Female,Bladder Diseases: epidemiology,Body Mass Index,Chi-Square Distribution,Cross-Sectional Studies,Human,Middle Aged,Odds Ratio,Prevalence,Risk Factors,Urinary Incontinence,Stress: epidemiology},
  language     = {eng},
  number       = {6},
  pages        = {600--604},
  publisher    = {Wiley-Blackwell},
  series       = {BJOG: An International Journal of Obstetrics & Gynaecology2000-01-01+01:00},
  title        = {Overactive bladder: prevalence, risk factors and relation to stress incontinence in middle-aged women.},
  url          = {http://dx.doi.org/10.1111/j.1471-0528.2004.00137.x},
  volume       = {111},
  year         = {2004},
}