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Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.

Thunander, Maria LU ; Petersson, C ; Jonzon, K ; Fornander, J ; Ossiansson, B ; Törn, Carina LU ; Edvardsson, S and Landin-Olsson, Mona LU (2008) In Diabetes Research and Clinical Practice 82. p.247-255
Abstract
All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide<0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were... (More)
All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide<0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were no gender differences in type 1 in any age group, small ones in pediatric subgroups. In type 2 men predominated in ages above 40 years. Incidences of type 1 diabetes in both children and adults were very high and as high above age 50 years as in children. Incidence of type 2 was the highest reported from Sweden, to which new diagnostic criteria, a high degree of case-finding, and many elders, may have contributed, but results may also reflect a true increase in incidence of both types of diabetes. (Less)
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetes Research and Clinical Practice
volume
82
pages
247 - 255
publisher
Elsevier
external identifiers
  • wos:000261597600015
  • pmid:18804305
  • scopus:54949099207
ISSN
1872-8227
DOI
10.1016/j.diabres.2008.07.022
language
English
LU publication?
yes
id
765fc2d7-8536-4b9d-9023-95a7f8f04a3f (old id 1242864)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18804305?dopt=Abstract
date added to LUP
2016-04-04 07:44:00
date last changed
2024-12-08 20:32:01
@article{765fc2d7-8536-4b9d-9023-95a7f8f04a3f,
  abstract     = {{All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab and/or ICA and/or C-peptide&lt;0.25nmol/L (0.7%) were classified as type 1 diabetes, the remaining as type 2. Incidence of type 1 in 0-19-year-olds was 37.8(36.1-39.6, 95%CI) and in 20-100 year-olds 27.1(25.6-27.4) per 100 000 and year, it was bimodal with equal peaks in 0-9 year-olds and in 50-80-year-olds. Adults had type 2 incidence 378 (375-380), children 3.1 (2.6-3.6). Among adults 6.9% had type 1 and 93.1% type 2. Among antibodypositive adults (n=101), GADab were present in 90%, ICA in 71%, both GADab and ICA in 61%. Ophthalmology contact as second source was confirmed for 98%. There were no gender differences in type 1 in any age group, small ones in pediatric subgroups. In type 2 men predominated in ages above 40 years. Incidences of type 1 diabetes in both children and adults were very high and as high above age 50 years as in children. Incidence of type 2 was the highest reported from Sweden, to which new diagnostic criteria, a high degree of case-finding, and many elders, may have contributed, but results may also reflect a true increase in incidence of both types of diabetes.}},
  author       = {{Thunander, Maria and Petersson, C and Jonzon, K and Fornander, J and Ossiansson, B and Törn, Carina and Edvardsson, S and Landin-Olsson, Mona}},
  issn         = {{1872-8227}},
  language     = {{eng}},
  pages        = {{247--255}},
  publisher    = {{Elsevier}},
  series       = {{Diabetes Research and Clinical Practice}},
  title        = {{Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden.}},
  url          = {{http://dx.doi.org/10.1016/j.diabres.2008.07.022}},
  doi          = {{10.1016/j.diabres.2008.07.022}},
  volume       = {{82}},
  year         = {{2008}},
}