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A correlation found between gold concentration in blood and patch test reactions in patients with coronary stents.

Ekqvist, Susanne LU ; Svedman, Cecilia LU ; Lundh, Thomas LU ; Möller, Halvon; Björk, Jonas LU and Bruze, Magnus LU (2008) In Contact Dermatitis 59(3). p.137-142
Abstract
BACKGROUND: Patients with dental gold restorations are known to have a higher level of gold concentration in blood (B-Au). OBJECTIVES: To further investigate, in a study on patients with intracoronary stents and contact allergy to metals, the gold and nickel release from stainless steel stent with (Au stent) and without (Ni stent) gold plating. METHOD: A total of 460 patients treated with stenting underwent patch testing with metals, and information on gold and nickel exposure and blood samples were collected. About 200 blood samples were randomly selected and the analysis of B-Au and nickel concentration in blood (B-Ni) was made using inductively coupled plasma mass spectrometry. RESULTS: There was a correlation between the intensity of... (More)
BACKGROUND: Patients with dental gold restorations are known to have a higher level of gold concentration in blood (B-Au). OBJECTIVES: To further investigate, in a study on patients with intracoronary stents and contact allergy to metals, the gold and nickel release from stainless steel stent with (Au stent) and without (Ni stent) gold plating. METHOD: A total of 460 patients treated with stenting underwent patch testing with metals, and information on gold and nickel exposure and blood samples were collected. About 200 blood samples were randomly selected and the analysis of B-Au and nickel concentration in blood (B-Ni) was made using inductively coupled plasma mass spectrometry. RESULTS: There was a correlation between the intensity of Au patch test reaction and B-Au (P < 0.001). This correlation could not be seen between Ni patch test reaction and B-Ni. A Au stent gave a fivefold higher B-Au than a Ni stent. CONCLUSIONS: Gold is released from the Au stent and patients with a Au stent have a fivefold higher B-Au than patients with an Ni stent. The patch test reactions for gold were correlated with B-Au. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Contact Dermatitis
volume
59
issue
3
pages
137 - 142
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000258728400002
  • pmid:18759893
  • scopus:50249136620
ISSN
0105-1873
DOI
10.1111/j.1600-0536.2008.01401.x
language
English
LU publication?
yes
id
cb32dd04-a5c8-4ff0-9170-b71e88874a88 (old id 1243598)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18759893?dopt=Abstract
date added to LUP
2008-10-03 15:00:52
date last changed
2017-01-01 07:30:47
@article{cb32dd04-a5c8-4ff0-9170-b71e88874a88,
  abstract     = {BACKGROUND: Patients with dental gold restorations are known to have a higher level of gold concentration in blood (B-Au). OBJECTIVES: To further investigate, in a study on patients with intracoronary stents and contact allergy to metals, the gold and nickel release from stainless steel stent with (Au stent) and without (Ni stent) gold plating. METHOD: A total of 460 patients treated with stenting underwent patch testing with metals, and information on gold and nickel exposure and blood samples were collected. About 200 blood samples were randomly selected and the analysis of B-Au and nickel concentration in blood (B-Ni) was made using inductively coupled plasma mass spectrometry. RESULTS: There was a correlation between the intensity of Au patch test reaction and B-Au (P &lt; 0.001). This correlation could not be seen between Ni patch test reaction and B-Ni. A Au stent gave a fivefold higher B-Au than a Ni stent. CONCLUSIONS: Gold is released from the Au stent and patients with a Au stent have a fivefold higher B-Au than patients with an Ni stent. The patch test reactions for gold were correlated with B-Au.},
  author       = {Ekqvist, Susanne and Svedman, Cecilia and Lundh, Thomas and Möller, Halvon and Björk, Jonas and Bruze, Magnus},
  issn         = {0105-1873},
  language     = {eng},
  number       = {3},
  pages        = {137--142},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {A correlation found between gold concentration in blood and patch test reactions in patients with coronary stents.},
  url          = {http://dx.doi.org/10.1111/j.1600-0536.2008.01401.x},
  volume       = {59},
  year         = {2008},
}