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Energy-driven asymmetric partitioning of a semiflexible polymer between interconnected cavities

Cifra, Peter; Linse, Per LU and Nies, Erik (2008) In The Journal of Physical Chemistry Part B 112(30). p.8923-8927
Abstract
The distribution of a semiflexible chain in the volume of two interconnected spherical cavities of equal size has been investigated by using Monte Carlo simulations. The chain possessed an extension exceeding that of the cavity, leading to large probabilities of translocated states despite the entropic penalty of passing the narrow passage. Furthermore, an asymmetric state with unequal subchain lengths in the two cavities was more favorable than the symmetric state. The preference for the asymmetric state is driven by the bending energy. Basically, in the symmetric state both subchains are forced to be bent, whereas in the asymmetric case only one of the subchains must bend, leading to an overall smaller bending penalty and overall smaller... (More)
The distribution of a semiflexible chain in the volume of two interconnected spherical cavities of equal size has been investigated by using Monte Carlo simulations. The chain possessed an extension exceeding that of the cavity, leading to large probabilities of translocated states despite the entropic penalty of passing the narrow passage. Furthermore, an asymmetric state with unequal subchain lengths in the two cavities was more favorable than the symmetric state. The preference for the asymmetric state is driven by the bending energy. Basically, in the symmetric state both subchains are forced to be bent, whereas in the asymmetric case only one of the subchains must bend, leading to an overall smaller bending penalty and overall smaller free energy of the asymmetric state. These results are in contrast to the entropy-controlled partitioning of polymers into confinement and the symmetric translocation state appearing for flexible polymers. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Journal of Physical Chemistry Part B
volume
112
issue
30
pages
8923 - 8927
publisher
The American Chemical Society
external identifiers
  • wos:000257926800013
  • scopus:49349116518
ISSN
1520-5207
DOI
10.1021/jp801782p
language
English
LU publication?
yes
id
9cf47e0f-abb9-473a-b24a-b7038bd7bf64 (old id 1253658)
date added to LUP
2008-10-28 15:44:31
date last changed
2017-01-01 05:20:10
@article{9cf47e0f-abb9-473a-b24a-b7038bd7bf64,
  abstract     = {The distribution of a semiflexible chain in the volume of two interconnected spherical cavities of equal size has been investigated by using Monte Carlo simulations. The chain possessed an extension exceeding that of the cavity, leading to large probabilities of translocated states despite the entropic penalty of passing the narrow passage. Furthermore, an asymmetric state with unequal subchain lengths in the two cavities was more favorable than the symmetric state. The preference for the asymmetric state is driven by the bending energy. Basically, in the symmetric state both subchains are forced to be bent, whereas in the asymmetric case only one of the subchains must bend, leading to an overall smaller bending penalty and overall smaller free energy of the asymmetric state. These results are in contrast to the entropy-controlled partitioning of polymers into confinement and the symmetric translocation state appearing for flexible polymers.},
  author       = {Cifra, Peter and Linse, Per and Nies, Erik},
  issn         = {1520-5207},
  language     = {eng},
  number       = {30},
  pages        = {8923--8927},
  publisher    = {The American Chemical Society},
  series       = {The Journal of Physical Chemistry Part B},
  title        = {Energy-driven asymmetric partitioning of a semiflexible polymer between interconnected cavities},
  url          = {http://dx.doi.org/10.1021/jp801782p},
  volume       = {112},
  year         = {2008},
}