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Saccharomyces kluyveri as a model organism to study pyrimidine degradation.

Beck, Halfdan LU ; Dobritzsch, Doreen and Piskur, Jure LU (2008) In FEMS Yeast Research 8(8). p.1209-1213
Abstract
Abstract The yeast Saccharomyces kluyveri (Lachancea kluyveri), a far relative of Saccharomyces cerevisiae, is not a widely studied organism in the laboratory. However, significant contributions to the understanding of nucleic acid precursors degradation in eukaryotes have been made using this model organism. Here we review eukaryotic pyrimidine degradation with emphasis on the contributions made with S. kluyveri and how this increases our understanding of human disease. Additionally, we discuss the possibilities and limitations of this nonconventional yeast as a laboratory organism.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cancer, pyrimidine, nucleic acid precursors, structure–function relationship, nonconventional yeast
in
FEMS Yeast Research
volume
8
issue
8
pages
1209 - 1213
publisher
Elsevier
external identifiers
  • wos:000260537300001
  • scopus:55349093988
ISSN
1567-1364
DOI
10.1111/j.1567-1364.2008.00442.x
language
English
LU publication?
yes
id
03abcf3c-c891-4f19-b09f-0ee48f5a162f (old id 1262735)
date added to LUP
2008-11-27 13:54:26
date last changed
2017-10-22 03:46:14
@article{03abcf3c-c891-4f19-b09f-0ee48f5a162f,
  abstract     = {Abstract The yeast Saccharomyces kluyveri (Lachancea kluyveri), a far relative of Saccharomyces cerevisiae, is not a widely studied organism in the laboratory. However, significant contributions to the understanding of nucleic acid precursors degradation in eukaryotes have been made using this model organism. Here we review eukaryotic pyrimidine degradation with emphasis on the contributions made with S. kluyveri and how this increases our understanding of human disease. Additionally, we discuss the possibilities and limitations of this nonconventional yeast as a laboratory organism.},
  author       = {Beck, Halfdan and Dobritzsch, Doreen and Piskur, Jure},
  issn         = {1567-1364},
  keyword      = {cancer,pyrimidine,nucleic acid precursors,structure–function relationship,nonconventional yeast},
  language     = {eng},
  number       = {8},
  pages        = {1209--1213},
  publisher    = {Elsevier},
  series       = {FEMS Yeast Research},
  title        = {Saccharomyces kluyveri as a model organism to study pyrimidine degradation.},
  url          = {http://dx.doi.org/10.1111/j.1567-1364.2008.00442.x},
  volume       = {8},
  year         = {2008},
}