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ACTH revisited - potential implications for patients with renal disease

Berg, Anna-Lena LU and Arnadottir, Margret (2000) In Nephrology Dialysis Transplantation 15(7). p.940-942
Abstract
Adrenocorticotrophic hormone (ACTH) facilitates the synthesis of adrenal glucocorticoids by maintaining the enzymes that control the side-chain cleavage of cholesterol, the rate-limiting step in the biosynthesis of steroids 1]. Thus, ACTH is involved in the control of adrenal lipid metabolism. Recent studies have revealed that treatment with ACTH in pharmacological dosage also influences plasma lipoprotein metabolism. This applies to both healthy individuals [2–4] and patients with different types of renal disease [5–7]. Moreover, the results of one of these recent studies suggest that treatment with ACTH has beneficial effects on the glomerular function of patients with idiopathic membranous nephropathy [7].
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nephrology Dialysis Transplantation
volume
15
issue
7
pages
940 - 942
publisher
Oxford University Press
external identifiers
  • scopus:0034126615
ISSN
1460-2385
DOI
10.1093/ndt/15.7.940
language
English
LU publication?
yes
id
bb05e58a-6346-47e3-8e67-40ba485f6658 (old id 1267096)
date added to LUP
2008-11-12 15:53:04
date last changed
2017-01-01 07:23:36
@article{bb05e58a-6346-47e3-8e67-40ba485f6658,
  abstract     = {Adrenocorticotrophic hormone (ACTH) facilitates the synthesis of adrenal glucocorticoids by maintaining the enzymes that control the side-chain cleavage of cholesterol, the rate-limiting step in the biosynthesis of steroids 1]. Thus, ACTH is involved in the control of adrenal lipid metabolism. Recent studies have revealed that treatment with ACTH in pharmacological dosage also influences plasma lipoprotein metabolism. This applies to both healthy individuals [2–4] and patients with different types of renal disease [5–7]. Moreover, the results of one of these recent studies suggest that treatment with ACTH has beneficial effects on the glomerular function of patients with idiopathic membranous nephropathy [7].},
  author       = {Berg, Anna-Lena and Arnadottir, Margret},
  issn         = {1460-2385},
  language     = {eng},
  number       = {7},
  pages        = {940--942},
  publisher    = {Oxford University Press},
  series       = {Nephrology Dialysis Transplantation},
  title        = {ACTH revisited - potential implications for patients with renal disease},
  url          = {http://dx.doi.org/10.1093/ndt/15.7.940},
  volume       = {15},
  year         = {2000},
}