Gender Differences in Predictors of Heart Failure Morbidity and Mortality in an Urban Swedish Population: The Malmo Preventive Project
(2008) In Open Heart Failure Journal 1. p.1-8- Abstract
- Objective/Background: Reports on heart failure (HF) predictors are scarce. We assessed gender-specific HF predictors.
Design: Preventive case-finding programme, register study.
Setting: City population-based sample.
Methods: We examined 33,342 HF-free subjects, 32.7% women, included in Malmo Preventive Project. Mean inclusion age was 49.7±7.4 years for women and 43.7±6.6 years for men.
Results: During 21.7±4.3 years of average follow-up, 764 (2.3%) subjects were diagnosed with HF, 120 (1.1%) women and 644 (2.9%) men. Following bootstrap analysis, the only strong independent predictor of HF among women was smoking. Independent predictors of HF among men were... (More) - Objective/Background: Reports on heart failure (HF) predictors are scarce. We assessed gender-specific HF predictors.
Design: Preventive case-finding programme, register study.
Setting: City population-based sample.
Methods: We examined 33,342 HF-free subjects, 32.7% women, included in Malmo Preventive Project. Mean inclusion age was 49.7±7.4 years for women and 43.7±6.6 years for men.
Results: During 21.7±4.3 years of average follow-up, 764 (2.3%) subjects were diagnosed with HF, 120 (1.1%) women and 644 (2.9%) men. Following bootstrap analysis, the only strong independent predictor of HF among women was smoking. Independent predictors of HF among men were diastolic blood pressure (BP), fasting blood-glucose, smoking, family history of myocardial infarction, and previous cardiovascular disease (CVD). During follow-up, 5,370 (16.1%) subjects died, 978 (9.0%) women and 4,392 (19.6%) men. Among both women and men, strong independent predictors of combined HF or all-cause death were high serum-triglycerides, fasting blood-glucose and estimated glomerular filtration rate, smoking, and previous CVD. Among men, also underweight, high BMI, and systolic and diastolic BP, were strong independent predictors of HF or death.
Conclusions: Although women and men shared many predictors of HF, there were several important differences between sexes. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1267649
- author
- Tasevska, Gordana LU ; Kennedy, Linn LU ; Anevski, Dragi LU ; Nilsson, Peter LU ; Christensson, Anders LU and Willenheimer, Ronnie LU
- organization
- publishing date
- 2008
- type
- Contribution to specialist publication or newspaper
- publication status
- published
- subject
- keywords
- Heart failure, mortality, predictors, men, women
- categories
- Popular Science
- in
- Open Heart Failure Journal
- volume
- 1
- pages
- 1 - 8
- publisher
- Bentham Open
- ISSN
- 1876-5351
- DOI
- 10.2174/1876535100801010001
- language
- English
- LU publication?
- yes
- id
- ede15cd0-b820-4120-ae28-cd52d360a62c (old id 1267649)
- alternative location
- http://www.benthamscience.com/open/tohfj/articles/V001/1TOHFJ.pdf
- date added to LUP
- 2016-04-01 13:03:22
- date last changed
- 2019-06-05 15:43:04
@misc{ede15cd0-b820-4120-ae28-cd52d360a62c, abstract = {{Objective/Background: Reports on heart failure (HF) predictors are scarce. We assessed gender-specific HF predictors.<br/><br> <br/><br> Design: Preventive case-finding programme, register study.<br/><br> <br/><br> Setting: City population-based sample.<br/><br> <br/><br> Methods: We examined 33,342 HF-free subjects, 32.7% women, included in Malmo Preventive Project. Mean inclusion age was 49.7±7.4 years for women and 43.7±6.6 years for men.<br/><br> <br/><br> Results: During 21.7±4.3 years of average follow-up, 764 (2.3%) subjects were diagnosed with HF, 120 (1.1%) women and 644 (2.9%) men. Following bootstrap analysis, the only strong independent predictor of HF among women was smoking. Independent predictors of HF among men were diastolic blood pressure (BP), fasting blood-glucose, smoking, family history of myocardial infarction, and previous cardiovascular disease (CVD). During follow-up, 5,370 (16.1%) subjects died, 978 (9.0%) women and 4,392 (19.6%) men. Among both women and men, strong independent predictors of combined HF or all-cause death were high serum-triglycerides, fasting blood-glucose and estimated glomerular filtration rate, smoking, and previous CVD. Among men, also underweight, high BMI, and systolic and diastolic BP, were strong independent predictors of HF or death.<br/><br> <br/><br> Conclusions: Although women and men shared many predictors of HF, there were several important differences between sexes.}}, author = {{Tasevska, Gordana and Kennedy, Linn and Anevski, Dragi and Nilsson, Peter and Christensson, Anders and Willenheimer, Ronnie}}, issn = {{1876-5351}}, keywords = {{Heart failure; mortality; predictors; men; women}}, language = {{eng}}, pages = {{1--8}}, publisher = {{Bentham Open}}, series = {{Open Heart Failure Journal}}, title = {{Gender Differences in Predictors of Heart Failure Morbidity and Mortality in an Urban Swedish Population: The Malmo Preventive Project}}, url = {{http://dx.doi.org/10.2174/1876535100801010001}}, doi = {{10.2174/1876535100801010001}}, volume = {{1}}, year = {{2008}}, }