The Factor V Leiden mutation is associated with a higher blood haemoglobin concentration in women below 50 of the Malmö Thrombophilia Study (MATS).
(2008) In Journal of Thrombosis and Thrombolysis Nov 21.- Abstract
- The aim of this study was to investigate a relationship between FVL-mutation and levels of haemoglobin (Hb) in patients with venous thromboembolism (VTE). From March 1998 to December 2005, 927 consecutive patients with objectively diagnosed VTE were registered in the Malmö Thrombophilia Study (MATS). Female patients with FVL-mutation below 50 years of age had significantly higher median-Hb (133 vs. 126 g/l; P < 0.001) compared to female patients below the age of 50 years without FVL. No significant difference could be found for men or women above 50 years of age or men below 50 years of age. Female patients below the age of 50 years with FVL-mutation and VTE are associated with higher median Hb, and this finding is in accordance with... (More)
- The aim of this study was to investigate a relationship between FVL-mutation and levels of haemoglobin (Hb) in patients with venous thromboembolism (VTE). From March 1998 to December 2005, 927 consecutive patients with objectively diagnosed VTE were registered in the Malmö Thrombophilia Study (MATS). Female patients with FVL-mutation below 50 years of age had significantly higher median-Hb (133 vs. 126 g/l; P < 0.001) compared to female patients below the age of 50 years without FVL. No significant difference could be found for men or women above 50 years of age or men below 50 years of age. Female patients below the age of 50 years with FVL-mutation and VTE are associated with higher median Hb, and this finding is in accordance with earlier hypothesis that FVL-mutation may have constituted an evolutionary selection advantage. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1271244
- author
- Isma, Nazim LU ; Breslin, Thomas LU ; Lindblad, Bengt LU and Svensson, Peter LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Thrombosis and Thrombolysis
- volume
- Nov 21
- publisher
- Springer
- external identifiers
-
- pmid:19023521
- scopus:70349141003
- ISSN
- 1573-742X
- DOI
- 10.1007/s11239-008-0293-z
- language
- English
- LU publication?
- yes
- id
- ce8839f2-74b1-4e91-9449-830463e2afda (old id 1271244)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19023521?dopt=Abstract
- date added to LUP
- 2016-04-04 09:19:39
- date last changed
- 2022-02-28 07:25:51
@article{ce8839f2-74b1-4e91-9449-830463e2afda, abstract = {{The aim of this study was to investigate a relationship between FVL-mutation and levels of haemoglobin (Hb) in patients with venous thromboembolism (VTE). From March 1998 to December 2005, 927 consecutive patients with objectively diagnosed VTE were registered in the Malmö Thrombophilia Study (MATS). Female patients with FVL-mutation below 50 years of age had significantly higher median-Hb (133 vs. 126 g/l; P < 0.001) compared to female patients below the age of 50 years without FVL. No significant difference could be found for men or women above 50 years of age or men below 50 years of age. Female patients below the age of 50 years with FVL-mutation and VTE are associated with higher median Hb, and this finding is in accordance with earlier hypothesis that FVL-mutation may have constituted an evolutionary selection advantage.}}, author = {{Isma, Nazim and Breslin, Thomas and Lindblad, Bengt and Svensson, Peter}}, issn = {{1573-742X}}, language = {{eng}}, publisher = {{Springer}}, series = {{Journal of Thrombosis and Thrombolysis}}, title = {{The Factor V Leiden mutation is associated with a higher blood haemoglobin concentration in women below 50 of the Malmö Thrombophilia Study (MATS).}}, url = {{https://lup.lub.lu.se/search/files/5294324/1368831.pdf}}, doi = {{10.1007/s11239-008-0293-z}}, volume = {{Nov 21}}, year = {{2008}}, }