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Comparison of patients undergoing enhanced external counterpulsation and spinal cord stimulation for refractory angina pectoris.

Bondesson, Susanne LU ; Pettersson, Tomas; Erdling, André; Rahm Hallberg, Ingalill LU ; Wackenfors, Angelica LU and Edvinsson, Lars LU (2008) In Coronary Artery Disease 19(8). p.627-634
Abstract
INTRODUCTION: As more patients survive coronary events, the prevalence of patients with refractory angina pectoris is increasing. The aim was to evaluate the effects of enhanced external counterpulsation (EECP) and spinal cord stimulation (SCS) and compare with optimal medically treated patients with refractory angina. METHODS: 153 patients with refractory angina were treated with either EECP, SCS, or were retained on their pharmacological treatment (control). Glyceryl trinitrate usage and Canadian Cardiovascular Society classification were registered at baseline, 6 and 12 months after therapy. RESULTS: Both EECP and SCS reduced the angina as compared with controls (P<0.001). Patients treated with EECP showed a more effective reduction... (More)
INTRODUCTION: As more patients survive coronary events, the prevalence of patients with refractory angina pectoris is increasing. The aim was to evaluate the effects of enhanced external counterpulsation (EECP) and spinal cord stimulation (SCS) and compare with optimal medically treated patients with refractory angina. METHODS: 153 patients with refractory angina were treated with either EECP, SCS, or were retained on their pharmacological treatment (control). Glyceryl trinitrate usage and Canadian Cardiovascular Society classification were registered at baseline, 6 and 12 months after therapy. RESULTS: Both EECP and SCS reduced the angina as compared with controls (P<0.001). Patients treated with EECP showed a more effective reduction as compared with SCS patients (P<0.05). Both treatments resulted in significantly decreased glyceryl trinitrate usage at 6 and 12 months follow-up (P<0.001). The nitrate consumed was unaltered in the controls. DISCUSSION: The results from this study show that both EECP and SCS therapy reduce angina in patients with refractory angina pectoris; the response to EECP was slightly more effective than that to SCS. Thus, EECP can be used as an alternative treatment for patients not responding to electrical stimulation. The beneficial effects in the treated groups were maintained during the 12 months follow-up period. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Coronary Artery Disease
volume
19
issue
8
pages
627 - 634
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000261257200013
  • pmid:19005298
  • scopus:56849091204
ISSN
0954-6928
DOI
10.1097/MCA.0b013e3283162489
language
English
LU publication?
yes
id
6f2c11ae-f052-4414-9226-bfb68f390c7a (old id 1271519)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19005298?dopt=Abstract
date added to LUP
2008-12-04 14:41:17
date last changed
2017-01-01 07:48:58
@article{6f2c11ae-f052-4414-9226-bfb68f390c7a,
  abstract     = {INTRODUCTION: As more patients survive coronary events, the prevalence of patients with refractory angina pectoris is increasing. The aim was to evaluate the effects of enhanced external counterpulsation (EECP) and spinal cord stimulation (SCS) and compare with optimal medically treated patients with refractory angina. METHODS: 153 patients with refractory angina were treated with either EECP, SCS, or were retained on their pharmacological treatment (control). Glyceryl trinitrate usage and Canadian Cardiovascular Society classification were registered at baseline, 6 and 12 months after therapy. RESULTS: Both EECP and SCS reduced the angina as compared with controls (P&lt;0.001). Patients treated with EECP showed a more effective reduction as compared with SCS patients (P&lt;0.05). Both treatments resulted in significantly decreased glyceryl trinitrate usage at 6 and 12 months follow-up (P&lt;0.001). The nitrate consumed was unaltered in the controls. DISCUSSION: The results from this study show that both EECP and SCS therapy reduce angina in patients with refractory angina pectoris; the response to EECP was slightly more effective than that to SCS. Thus, EECP can be used as an alternative treatment for patients not responding to electrical stimulation. The beneficial effects in the treated groups were maintained during the 12 months follow-up period.},
  author       = {Bondesson, Susanne and Pettersson, Tomas and Erdling, André and Rahm Hallberg, Ingalill and Wackenfors, Angelica and Edvinsson, Lars},
  issn         = {0954-6928},
  language     = {eng},
  number       = {8},
  pages        = {627--634},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Coronary Artery Disease},
  title        = {Comparison of patients undergoing enhanced external counterpulsation and spinal cord stimulation for refractory angina pectoris.},
  url          = {http://dx.doi.org/10.1097/MCA.0b013e3283162489},
  volume       = {19},
  year         = {2008},
}