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Left atrioventricular plane displacement but not left ventricular ejection fraction is influenced by the degree of aortic stenosis.

Rydberg, Erik LU ; Gudmundsson, P; Kennedy, Linn LU ; Erhardt, Leif RW LU and Willenheimer, Ronnie LU (2004) In Heart 90(10). p.5-1151
Abstract (Swedish)
Abstract in Undetermined

Aims: To examine how left atrioventricular plane displacement ( AVPD), a widely used measure of left ventricular (LV) function, is related to presence and degree of aortic stenosis. Methods and results: Cardiac dimensions, LV filling, left AVPD, LV ejection fraction (LVEF), and valve function were assessed by echocardiography/Doppler in 182 patients with various cardiac diseases (mean (SD) age 69 (12) years, 36% women), 49 consecutive with and 133 consecutive without aortic stenosis. In an analysis of covariance, neither left AVPD nor LVEF was independently correlated with the presence of aortic stenosis. However, looking separately at patients with aortic stenosis, left AVPD (p = 0.03) but not LVEF... (More)
Abstract in Undetermined

Aims: To examine how left atrioventricular plane displacement ( AVPD), a widely used measure of left ventricular (LV) function, is related to presence and degree of aortic stenosis. Methods and results: Cardiac dimensions, LV filling, left AVPD, LV ejection fraction (LVEF), and valve function were assessed by echocardiography/Doppler in 182 patients with various cardiac diseases (mean (SD) age 69 (12) years, 36% women), 49 consecutive with and 133 consecutive without aortic stenosis. In an analysis of covariance, neither left AVPD nor LVEF was independently correlated with the presence of aortic stenosis. However, looking separately at patients with aortic stenosis, left AVPD (p = 0.03) but not LVEF correlated independently with degree of aortic stenosis in multiple linear regression analysis. In patients with aortic stenosis, an abnormal left AVPD had 94% sensitivity and 90% negative predictive value with regard to severe aortic stenosis, compared with 56% and 62%, respectively, for LVEF. Conclusion: In patients with cardiac disease, neither left AVPD nor LVEF correlated independently with presence of aortic stenosis. However, in patients with aortic stenosis, left AVPD but not LVEF correlated with the degree of aortic valve obstruction and left AVPD but not LVEF had high sensitivity and negative predictive value with regard to severe aortic stenosis. Compared with LVEF, left AVPD is an earlier and more sensitive marker of LV haemodynamic load in patients with aortic stenosis. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Heart
volume
90
issue
10
pages
5 - 1151
publisher
BMJ Publishing Group
external identifiers
  • pmid:15367511
  • wos:000223861900011
  • scopus:4644336981
ISSN
1355-6037
DOI
10.1136/hrt.2003.020628
language
English
LU publication?
yes
id
10f3d6d6-b8f0-415d-8370-8d96584dae93 (old id 127389)
alternative location
http://heart.bmjjournals.com/cgi/content/abstract/90/10/1151
date added to LUP
2007-07-30 14:49:39
date last changed
2017-12-10 03:54:07
@article{10f3d6d6-b8f0-415d-8370-8d96584dae93,
  abstract     = {<b>Abstract in Undetermined</b><br/><br>
Aims: To examine how left atrioventricular plane displacement ( AVPD), a widely used measure of left ventricular (LV) function, is related to presence and degree of aortic stenosis. Methods and results: Cardiac dimensions, LV filling, left AVPD, LV ejection fraction (LVEF), and valve function were assessed by echocardiography/Doppler in 182 patients with various cardiac diseases (mean (SD) age 69 (12) years, 36% women), 49 consecutive with and 133 consecutive without aortic stenosis. In an analysis of covariance, neither left AVPD nor LVEF was independently correlated with the presence of aortic stenosis. However, looking separately at patients with aortic stenosis, left AVPD (p = 0.03) but not LVEF correlated independently with degree of aortic stenosis in multiple linear regression analysis. In patients with aortic stenosis, an abnormal left AVPD had 94% sensitivity and 90% negative predictive value with regard to severe aortic stenosis, compared with 56% and 62%, respectively, for LVEF. Conclusion: In patients with cardiac disease, neither left AVPD nor LVEF correlated independently with presence of aortic stenosis. However, in patients with aortic stenosis, left AVPD but not LVEF correlated with the degree of aortic valve obstruction and left AVPD but not LVEF had high sensitivity and negative predictive value with regard to severe aortic stenosis. Compared with LVEF, left AVPD is an earlier and more sensitive marker of LV haemodynamic load in patients with aortic stenosis.},
  author       = {Rydberg, Erik and Gudmundsson, P and Kennedy, Linn and Erhardt, Leif RW and Willenheimer, Ronnie},
  issn         = {1355-6037},
  language     = {eng},
  number       = {10},
  pages        = {5--1151},
  publisher    = {BMJ Publishing Group},
  series       = {Heart},
  title        = {Left atrioventricular plane displacement but not left ventricular ejection fraction is influenced by the degree of aortic stenosis.},
  url          = {http://dx.doi.org/10.1136/hrt.2003.020628},
  volume       = {90},
  year         = {2004},
}