Hand muscle pathology after long-term vibration exposure.
(2004) In Journal of Hand Surgery (British Volume) 29(5). p.431-437- Abstract
- The morphology of the abductor pollicis brevis muscle was studied in 20 patients suffering from hand-arm vibration syndrome. The main morphological changes observed were centrally located myonuclei and fibre type grouping (found in all 20 muscle biopsies), angulated muscle fibres (found in 19 biopsies), ring fibres and regenerating fibres (found in 18 biopsies) and fibrosis (found in 17 biopsies). The observed abnormalities are believed to reflect damage to both the muscle fibres and the motor nerve. The changes were related to different vibration exposure parameters. The number of fibres demonstrating centrally located nuclei correlated significantly with the cumulative vibration exposure, while the number of angulated fibres correlated... (More)
- The morphology of the abductor pollicis brevis muscle was studied in 20 patients suffering from hand-arm vibration syndrome. The main morphological changes observed were centrally located myonuclei and fibre type grouping (found in all 20 muscle biopsies), angulated muscle fibres (found in 19 biopsies), ring fibres and regenerating fibres (found in 18 biopsies) and fibrosis (found in 17 biopsies). The observed abnormalities are believed to reflect damage to both the muscle fibres and the motor nerve. The changes were related to different vibration exposure parameters. The number of fibres demonstrating centrally located nuclei correlated significantly with the cumulative vibration exposure, while the number of angulated fibres correlated significantly with the total vibration exposure time. This indicates that the vibrating tools may cause direct damage to muscle fibres as well as nerves. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/127693
- author
- Necking, Lars LU ; Lundborg, Göran LU ; Lundström, Ronnie ; Thornell, Lars-Eric and Fridén, Jan
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- exposure time, total vibration, hand-arm vibration syndrome, muscle pathology, tool acceleration, CVE
- in
- Journal of Hand Surgery (British Volume)
- volume
- 29
- issue
- 5
- pages
- 431 - 437
- publisher
- SAGE Publications
- external identifiers
-
- wos:000224045800004
- pmid:15336744
- scopus:4444267737
- pmid:15336744
- ISSN
- 0266-7681
- DOI
- 10.1016/j.jhsb.2004.05.004
- language
- English
- LU publication?
- yes
- id
- 14f19e2a-71d1-4956-8e65-ca0ee218af17 (old id 127693)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15336744&dopt=Abstract
- date added to LUP
- 2016-04-01 16:02:24
- date last changed
- 2022-03-30 05:05:48
@article{14f19e2a-71d1-4956-8e65-ca0ee218af17,
abstract = {{The morphology of the abductor pollicis brevis muscle was studied in 20 patients suffering from hand-arm vibration syndrome. The main morphological changes observed were centrally located myonuclei and fibre type grouping (found in all 20 muscle biopsies), angulated muscle fibres (found in 19 biopsies), ring fibres and regenerating fibres (found in 18 biopsies) and fibrosis (found in 17 biopsies). The observed abnormalities are believed to reflect damage to both the muscle fibres and the motor nerve. The changes were related to different vibration exposure parameters. The number of fibres demonstrating centrally located nuclei correlated significantly with the cumulative vibration exposure, while the number of angulated fibres correlated significantly with the total vibration exposure time. This indicates that the vibrating tools may cause direct damage to muscle fibres as well as nerves.}},
author = {{Necking, Lars and Lundborg, Göran and Lundström, Ronnie and Thornell, Lars-Eric and Fridén, Jan}},
issn = {{0266-7681}},
keywords = {{exposure time; total vibration; hand-arm vibration syndrome; muscle pathology; tool acceleration; CVE}},
language = {{eng}},
number = {{5}},
pages = {{431--437}},
publisher = {{SAGE Publications}},
series = {{Journal of Hand Surgery (British Volume)}},
title = {{Hand muscle pathology after long-term vibration exposure.}},
url = {{http://dx.doi.org/10.1016/j.jhsb.2004.05.004}},
doi = {{10.1016/j.jhsb.2004.05.004}},
volume = {{29}},
year = {{2004}},
}