Base-catalyzed intramolecular condensation of tokinolide B.
(2003) In Tetrahedron Letters 44(12). p.2509-2512- Abstract
- The novel pentacyclic compound cyclotokinolide B was obtained from the natural phthalide tokinolide B under basic conditions, via the chemoselective -enol lactone opening followed by a Michael addition of the generated carbanion to the enone and subsequent equilibration. This result confirms that some dimeric phthalides undergo intramolecular cyclizations in basic media.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/127989
- author
- Quiroz-García, B ; Hernández, L ; Toscano, R A ; Sterner, Olov LU and Delgado, G
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Tetrahedron Letters
- volume
- 44
- issue
- 12
- pages
- 2509 - 2512
- publisher
- Elsevier
- external identifiers
-
- wos:000181575200017
- scopus:0037450919
- ISSN
- 0040-4039
- DOI
- 10.1016/S0040-4039(03)00291-0
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
- id
- 762c5706-98a5-4346-a9ec-761f5997f784 (old id 127989)
- date added to LUP
- 2016-04-01 16:31:06
- date last changed
- 2022-01-28 20:17:42
@article{762c5706-98a5-4346-a9ec-761f5997f784, abstract = {{The novel pentacyclic compound cyclotokinolide B was obtained from the natural phthalide tokinolide B under basic conditions, via the chemoselective -enol lactone opening followed by a Michael addition of the generated carbanion to the enone and subsequent equilibration. This result confirms that some dimeric phthalides undergo intramolecular cyclizations in basic media.}}, author = {{Quiroz-García, B and Hernández, L and Toscano, R A and Sterner, Olov and Delgado, G}}, issn = {{0040-4039}}, language = {{eng}}, number = {{12}}, pages = {{2509--2512}}, publisher = {{Elsevier}}, series = {{Tetrahedron Letters}}, title = {{Base-catalyzed intramolecular condensation of tokinolide B.}}, url = {{http://dx.doi.org/10.1016/S0040-4039(03)00291-0}}, doi = {{10.1016/S0040-4039(03)00291-0}}, volume = {{44}}, year = {{2003}}, }