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Thrombus Embolization Into IVC Filters During Catheter-Directed Thrombolysis for Proximal Deep Venous Thrombosis

Kölbel, Tilo LU ; Alhadad, Alaa LU ; Acosta, Stefan LU ; Lindh, Mats LU ; Ivancev, Krasnodar and Gottsäter, Anders LU (2008) In Journal of Endovascular Therapy 15(5). p.605-613
Abstract
Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than... (More)
Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than in patients without a hypercoagulable disorder (n=11, 69%; OR 0.1, 95% Cl 0.02 to 0.56, p=0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter. Conclusion: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
IVC, inferior vena cava, thrombolysis, deep venous thrombosis, thrombus, hypercoagulable disorder, embolus, filter
in
Journal of Endovascular Therapy
volume
15
issue
5
pages
605 - 613
publisher
International Society of Endovascular Specialists
external identifiers
  • wos:000260232200016
  • scopus:56349137725
ISSN
1545-1550
language
English
LU publication?
yes
id
8c90cb1b-44ad-4fb1-80e2-27ebcdcb10c3 (old id 1284904)
date added to LUP
2009-02-06 11:30:51
date last changed
2017-08-13 03:38:20
@article{8c90cb1b-44ad-4fb1-80e2-27ebcdcb10c3,
  abstract     = {Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than in patients without a hypercoagulable disorder (n=11, 69%; OR 0.1, 95% Cl 0.02 to 0.56, p=0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter. Conclusion: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism.},
  author       = {Kölbel, Tilo and Alhadad, Alaa and Acosta, Stefan and Lindh, Mats and Ivancev, Krasnodar and Gottsäter, Anders},
  issn         = {1545-1550},
  keyword      = {IVC,inferior vena cava,thrombolysis,deep venous thrombosis,thrombus,hypercoagulable disorder,embolus,filter},
  language     = {eng},
  number       = {5},
  pages        = {605--613},
  publisher    = {International Society of Endovascular Specialists},
  series       = {Journal of Endovascular Therapy},
  title        = {Thrombus Embolization Into IVC Filters During Catheter-Directed Thrombolysis for Proximal Deep Venous Thrombosis},
  volume       = {15},
  year         = {2008},
}