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Computer-assisted carotid plaque analysis: characteristics of plaques associated with cerebrovascular symptoms and cerebral infarction

Pedro, L M; Pedro, M M; Goncalves, Isabel LU ; Carneiro, T F; Balsinha, C; Fernandes e Fernandes, R and Fernandes e Fernandes, J (2000) In European Journal of Vascular and Endovascular Surgery 19(2). p.118-123
Abstract
OBJECTIVE: to correlate the echostructural characteristics of carotid plaques with neurological symptoms and cerebral infarcts. MATERIALS: one hundred and five plaques were studied in 74 patients by colour-flow duplex ultrasound: 39 were symptomatic and 37 were associated with brain infarction on CT scanning. METHODS: the images were digitalised for computer-assisted image standardisation and divided in homogenous (n=67) and heterogenous (n=38) groups. Parameters of the plaque image were analysed. RESULTS: global echogenicity was significantly lower in symptomatic and in CT(+)plaques (p<0.05). For homogenous plaques, an echogenic cap (EC) was visualised in 8.3% of symptomatic vs. 33.9% of asymptomatic (p<0. 05) and in 7.7% for... (More)
OBJECTIVE: to correlate the echostructural characteristics of carotid plaques with neurological symptoms and cerebral infarcts. MATERIALS: one hundred and five plaques were studied in 74 patients by colour-flow duplex ultrasound: 39 were symptomatic and 37 were associated with brain infarction on CT scanning. METHODS: the images were digitalised for computer-assisted image standardisation and divided in homogenous (n=67) and heterogenous (n=38) groups. Parameters of the plaque image were analysed. RESULTS: global echogenicity was significantly lower in symptomatic and in CT(+)plaques (p<0.05). For homogenous plaques, an echogenic cap (EC) was visualised in 8.3% of symptomatic vs. 33.9% of asymptomatic (p<0. 05) and in 7.7% for plaques that were CT(+)vs. 37.7% for CT(-)(p<0. 05). Surface disruption was visualised in 50% of symptomatic vs. 8. 5% of asymptomatic (p=0.002) and in 46% of CT(+)vs. 9.4% of CT(-)plaques (p=0.002). For heterogenous plaques, the echolucent region was juxtaluminal in 67% of symptomatic and CT(+)plaques vs. 33% in asymptomatic and CT(-)(p<0.01). CONCLUSION: echolucent plaques are associated with a higher neurological risk. In homogenous plaques the absence of an echogenic cap and disruption of the plaque surface also correlates with symptoms. In heterogenous plaques, juxtaluminal location of the echolucent region is an additional marker of increased risk. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Vascular and Endovascular Surgery
volume
19
issue
2
pages
118 - 123
publisher
Elsevier
external identifiers
  • wos:000086097100003
  • scopus:0034144251
ISSN
1532-2165
DOI
10.1053/ejvs.1999.0952
language
English
LU publication?
no
id
8f21a5a1-1d25-4e83-be8c-c30a4a6b0350 (old id 1296973)
date added to LUP
2009-07-15 12:46:08
date last changed
2017-07-09 04:19:02
@article{8f21a5a1-1d25-4e83-be8c-c30a4a6b0350,
  abstract     = {OBJECTIVE: to correlate the echostructural characteristics of carotid plaques with neurological symptoms and cerebral infarcts. MATERIALS: one hundred and five plaques were studied in 74 patients by colour-flow duplex ultrasound: 39 were symptomatic and 37 were associated with brain infarction on CT scanning. METHODS: the images were digitalised for computer-assisted image standardisation and divided in homogenous (n=67) and heterogenous (n=38) groups. Parameters of the plaque image were analysed. RESULTS: global echogenicity was significantly lower in symptomatic and in CT(+)plaques (p&lt;0.05). For homogenous plaques, an echogenic cap (EC) was visualised in 8.3% of symptomatic vs. 33.9% of asymptomatic (p&lt;0. 05) and in 7.7% for plaques that were CT(+)vs. 37.7% for CT(-)(p&lt;0. 05). Surface disruption was visualised in 50% of symptomatic vs. 8. 5% of asymptomatic (p=0.002) and in 46% of CT(+)vs. 9.4% of CT(-)plaques (p=0.002). For heterogenous plaques, the echolucent region was juxtaluminal in 67% of symptomatic and CT(+)plaques vs. 33% in asymptomatic and CT(-)(p&lt;0.01). CONCLUSION: echolucent plaques are associated with a higher neurological risk. In homogenous plaques the absence of an echogenic cap and disruption of the plaque surface also correlates with symptoms. In heterogenous plaques, juxtaluminal location of the echolucent region is an additional marker of increased risk.},
  author       = {Pedro, L M and Pedro, M M and Goncalves, Isabel and Carneiro, T F and Balsinha, C and Fernandes e Fernandes, R and Fernandes e Fernandes, J},
  issn         = {1532-2165},
  language     = {eng},
  number       = {2},
  pages        = {118--123},
  publisher    = {Elsevier},
  series       = {European Journal of Vascular and Endovascular Surgery},
  title        = {Computer-assisted carotid plaque analysis: characteristics of plaques associated with cerebrovascular symptoms and cerebral infarction},
  url          = {http://dx.doi.org/10.1053/ejvs.1999.0952},
  volume       = {19},
  year         = {2000},
}