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Pathogenesis of chronic pancreatitis: A comprehensive update and a look into the future.

Andersson, Roland LU ; Tingstedt, Bobby LU and Xia, Jinglin (2009) In Scandinavian Journal of Gastroenterology 44. p.661-663
Abstract
Chronic pancreatitis is a relatively frequent condition usually caused by alcoholic abuse but also due to recurrent gallstone disease, metabolic endocrine disorders and haemochromatosis, among others. Specific types such as hereditary and autoimmune pancreatitis should be particularly kept in mind and emphasized, as they require specific treatment and attention. The possibility to identify gene mutations has also increased and this is likely to decrease the overall total number of "idiopathic" chronic pancreatitis cases. Pancreatic stellate cells have been identified as potential key players in the progression of chronic pancreatitis and the development of fibrogenesis, which are activated either during repeated attacks of... (More)
Chronic pancreatitis is a relatively frequent condition usually caused by alcoholic abuse but also due to recurrent gallstone disease, metabolic endocrine disorders and haemochromatosis, among others. Specific types such as hereditary and autoimmune pancreatitis should be particularly kept in mind and emphasized, as they require specific treatment and attention. The possibility to identify gene mutations has also increased and this is likely to decrease the overall total number of "idiopathic" chronic pancreatitis cases. Pancreatic stellate cells have been identified as potential key players in the progression of chronic pancreatitis and the development of fibrogenesis, which are activated either during repeated attacks of necro-inflammation or directly by toxic factors. The inhibition or modulation of pancreatic stellate cells could represent a way of potential intervention in patients with chronic pancreatitis in the future. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Gastroenterology
volume
44
pages
661 - 663
publisher
Taylor & Francis
external identifiers
  • wos:000266199200002
  • pmid:19199163
  • scopus:67651148478
ISSN
1502-7708
DOI
10.1080/00365520902718739
language
English
LU publication?
yes
id
7fc9f4db-6ee7-417c-8dd8-77ca61168dc0 (old id 1302812)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19199163?dopt=Abstract
date added to LUP
2009-03-02 15:40:46
date last changed
2017-01-01 07:50:22
@article{7fc9f4db-6ee7-417c-8dd8-77ca61168dc0,
  abstract     = {Chronic pancreatitis is a relatively frequent condition usually caused by alcoholic abuse but also due to recurrent gallstone disease, metabolic endocrine disorders and haemochromatosis, among others. Specific types such as hereditary and autoimmune pancreatitis should be particularly kept in mind and emphasized, as they require specific treatment and attention. The possibility to identify gene mutations has also increased and this is likely to decrease the overall total number of "idiopathic" chronic pancreatitis cases. Pancreatic stellate cells have been identified as potential key players in the progression of chronic pancreatitis and the development of fibrogenesis, which are activated either during repeated attacks of necro-inflammation or directly by toxic factors. The inhibition or modulation of pancreatic stellate cells could represent a way of potential intervention in patients with chronic pancreatitis in the future.},
  author       = {Andersson, Roland and Tingstedt, Bobby and Xia, Jinglin},
  issn         = {1502-7708},
  language     = {eng},
  pages        = {661--663},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Gastroenterology},
  title        = {Pathogenesis of chronic pancreatitis: A comprehensive update and a look into the future.},
  url          = {http://dx.doi.org/10.1080/00365520902718739},
  volume       = {44},
  year         = {2009},
}