Male Circumcision and Serologically Determined Human Papillomavirus Infection in a Birth Cohort
(2009) In Cancer Epidemiology Biomarkers & Prevention 18(1). p.177-183- Abstract
- Circumcision has been reported to protect against infection with human papillomavirus (HPV) in men, but results have been inconsistent. We followed males in a birth cohort born in Dunedin, New Zealand, in 1972 and 1973 from age 3 to 32 years. Seropositivity at age 32 years for the oncogenic types HPV-16 and 18, and the nononcogenic types 6 and 11, was studied in relation to maternal reports of circumcision status at age 3 for 450 men. Seropositivity to any of these types was associated with lifetime number of sexual partners (P = 0.03), and lower moral-religious emphasis of the family of origin (P < 0.001). Circumcision was not found to be protective, with the adjusted odds ratio (95% confidence interval) for HPV6/11/16/18... (More)
- Circumcision has been reported to protect against infection with human papillomavirus (HPV) in men, but results have been inconsistent. We followed males in a birth cohort born in Dunedin, New Zealand, in 1972 and 1973 from age 3 to 32 years. Seropositivity at age 32 years for the oncogenic types HPV-16 and 18, and the nononcogenic types 6 and 11, was studied in relation to maternal reports of circumcision status at age 3 for 450 men. Seropositivity to any of these types was associated with lifetime number of sexual partners (P = 0.03), and lower moral-religious emphasis of the family of origin (P < 0.001). Circumcision was not found to be protective, with the adjusted odds ratio (95% confidence interval) for HPV6/11/16/18 seropositivity among the circumcised compared with the uncircumcised being 1.4 (0.89-2.2). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1312859
- author
- Dickson, Nigel P. ; Ryding, Janka LU ; van Roode, Thea ; Paul, Charlotte ; Herbison, Peter ; Dillner, Joakim LU and Skegg, David C. G.
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cancer Epidemiology Biomarkers & Prevention
- volume
- 18
- issue
- 1
- pages
- 177 - 183
- publisher
- American Association for Cancer Research
- external identifiers
-
- wos:000262424200023
- scopus:58349091479
- pmid:19124496
- ISSN
- 1538-7755
- DOI
- 10.1158/1055-9965.EPI-08-0353
- language
- English
- LU publication?
- yes
- id
- 3e6f33c8-89ae-49a3-add4-62e2d8de646c (old id 1312859)
- date added to LUP
- 2016-04-01 13:45:11
- date last changed
- 2022-01-27 20:53:54
@article{3e6f33c8-89ae-49a3-add4-62e2d8de646c,
abstract = {{Circumcision has been reported to protect against infection with human papillomavirus (HPV) in men, but results have been inconsistent. We followed males in a birth cohort born in Dunedin, New Zealand, in 1972 and 1973 from age 3 to 32 years. Seropositivity at age 32 years for the oncogenic types HPV-16 and 18, and the nononcogenic types 6 and 11, was studied in relation to maternal reports of circumcision status at age 3 for 450 men. Seropositivity to any of these types was associated with lifetime number of sexual partners (P = 0.03), and lower moral-religious emphasis of the family of origin (P < 0.001). Circumcision was not found to be protective, with the adjusted odds ratio (95% confidence interval) for HPV6/11/16/18 seropositivity among the circumcised compared with the uncircumcised being 1.4 (0.89-2.2).}},
author = {{Dickson, Nigel P. and Ryding, Janka and van Roode, Thea and Paul, Charlotte and Herbison, Peter and Dillner, Joakim and Skegg, David C. G.}},
issn = {{1538-7755}},
language = {{eng}},
number = {{1}},
pages = {{177--183}},
publisher = {{American Association for Cancer Research}},
series = {{Cancer Epidemiology Biomarkers & Prevention}},
title = {{Male Circumcision and Serologically Determined Human Papillomavirus Infection in a Birth Cohort}},
url = {{http://dx.doi.org/10.1158/1055-9965.EPI-08-0353}},
doi = {{10.1158/1055-9965.EPI-08-0353}},
volume = {{18}},
year = {{2009}},
}