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Interaction between weak low frequency magnetic fields and cell membranes.

Baureus Koch, Catrin LU ; Sommarin, Marianne LU ; Persson, Bertil R LU ; Salford, Leif LU and Eberhardt, Jacob LU (2003) In Bioelectromagnetics 24(6). p.395-402
Abstract
The question of whether very weak low frequency magnetic fields can affect biological systems, has attracted attention by many research groups for quite some time. Still, today, the theoretical possibility of such an interaction is often questioned and the site of interaction in the cell is unknown. In the present study, the influence of extremely low frequency (ELF) magnetic fields on the transport of Ca2+ was studied in a biological system consisting of highly purified plasma membrane vesicles. We tested two quantum mechanical theoretical models that assume that biologically active ions can be bound to a channel protein and influence the opening state of the channel. Vesicles were exposed for 30 min at 32 °C and the calcium efflux was... (More)
The question of whether very weak low frequency magnetic fields can affect biological systems, has attracted attention by many research groups for quite some time. Still, today, the theoretical possibility of such an interaction is often questioned and the site of interaction in the cell is unknown. In the present study, the influence of extremely low frequency (ELF) magnetic fields on the transport of Ca2+ was studied in a biological system consisting of highly purified plasma membrane vesicles. We tested two quantum mechanical theoretical models that assume that biologically active ions can be bound to a channel protein and influence the opening state of the channel. Vesicles were exposed for 30 min at 32 °C and the calcium efflux was studied using radioactive 45Ca as a tracer. Static magnetic fields ranging from 27 to 37 T and time varying magnetic fields with frequencies between 7 and 72 Hz and amplitudes between 13 and 114 T (peak) were used. We show that suitable combinations of static and time varying magnetic fields directly interact with the Ca2+ channel protein in the cell membrane, and we could quantitatively confirm the model proposed by Blanchard. Bioelectromagnetics 24:395-402, 2003. © 2003 Wiley-Liss, Inc. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bioelectromagnetics
volume
24
issue
6
pages
395 - 402
publisher
John Wiley & Sons
external identifiers
  • wos:000185026900004
  • scopus:2142742778
ISSN
0197-8462
DOI
10.1002/bem.10136
language
English
LU publication?
yes
id
f0b8e160-f1de-4e98-bd9b-627372b04439 (old id 132656)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12929158&dopt=Abstract
date added to LUP
2007-07-04 11:19:55
date last changed
2018-09-30 03:29:10
@article{f0b8e160-f1de-4e98-bd9b-627372b04439,
  abstract     = {The question of whether very weak low frequency magnetic fields can affect biological systems, has attracted attention by many research groups for quite some time. Still, today, the theoretical possibility of such an interaction is often questioned and the site of interaction in the cell is unknown. In the present study, the influence of extremely low frequency (ELF) magnetic fields on the transport of Ca2+ was studied in a biological system consisting of highly purified plasma membrane vesicles. We tested two quantum mechanical theoretical models that assume that biologically active ions can be bound to a channel protein and influence the opening state of the channel. Vesicles were exposed for 30 min at 32 °C and the calcium efflux was studied using radioactive 45Ca as a tracer. Static magnetic fields ranging from 27 to 37 T and time varying magnetic fields with frequencies between 7 and 72 Hz and amplitudes between 13 and 114 T (peak) were used. We show that suitable combinations of static and time varying magnetic fields directly interact with the Ca2+ channel protein in the cell membrane, and we could quantitatively confirm the model proposed by Blanchard. Bioelectromagnetics 24:395-402, 2003. © 2003 Wiley-Liss, Inc.},
  author       = {Baureus Koch, Catrin and Sommarin, Marianne and Persson, Bertil R and Salford, Leif and Eberhardt, Jacob},
  issn         = {0197-8462},
  language     = {eng},
  number       = {6},
  pages        = {395--402},
  publisher    = {John Wiley & Sons},
  series       = {Bioelectromagnetics},
  title        = {Interaction between weak low frequency magnetic fields and cell membranes.},
  url          = {http://dx.doi.org/10.1002/bem.10136},
  volume       = {24},
  year         = {2003},
}