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Linkage between nuclear and mitochondrial DNA sequences in avian malaria parasites: Multiple cases of cryptic speciation?

Bensch, Staffan LU ; Perez-Tris, Javier LU ; Waldenström, Jonas LU and Hellgren, Olof LU (2004) In Evolution 58(7). p.1617-1621
Abstract
Analyses of mitochondrial cytochrome b diversity among avian blood parasites of the genera Haemoproteus and Plasmodium suggest that there might be as many lineages of parasites as there are species of birds. This is in sharp contrast to the approximately 175 parasite species described by traditional methods based on morphology using light microscopy. Until now it has not been clear to what extent parasite mitochondrial DNA lineage diversity reflects intra- or interspecific variation. We have sequenced part of a fast-evolving nuclear gene, dihydrofolate reductase-thymidylate synthase (DHFR-TS), and demonstrate that most of the parasite mitochondrial DNA lineages are associated with unique gene copies at this locus. Although these parasite... (More)
Analyses of mitochondrial cytochrome b diversity among avian blood parasites of the genera Haemoproteus and Plasmodium suggest that there might be as many lineages of parasites as there are species of birds. This is in sharp contrast to the approximately 175 parasite species described by traditional methods based on morphology using light microscopy. Until now it has not been clear to what extent parasite mitochondrial DNA lineage diversity reflects intra- or interspecific variation. We have sequenced part of a fast-evolving nuclear gene, dihydrofolate reductase-thymidylate synthase (DHFR-TS), and demonstrate that most of the parasite mitochondrial DNA lineages are associated with unique gene copies at this locus. Although these parasite lineages sometimes coexist in the same host individual, they apparently do not recombine and could therefore be considered as functionally distinct evolutionary entities, with independent evolutionary potential. Studies examining parasite virulence and host immune systems must consider this remarkable diversity of avian malaria parasites. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Evolution
volume
58
issue
7
pages
1617 - 1621
publisher
Wiley-Blackwell
external identifiers
  • pmid:15341164
  • wos:000222982800021
  • scopus:3843091789
ISSN
1558-5646
language
English
LU publication?
yes
id
c88d61c5-b735-451f-a59c-b469d3ef5368 (old id 136943)
alternative location
http://evol.allenpress.com/evolonline/?request=get-abstract&issn=0014-3820&volume=058&issue=07&page=1617
date added to LUP
2007-06-25 13:00:39
date last changed
2017-11-12 04:03:32
@article{c88d61c5-b735-451f-a59c-b469d3ef5368,
  abstract     = {Analyses of mitochondrial cytochrome b diversity among avian blood parasites of the genera Haemoproteus and Plasmodium suggest that there might be as many lineages of parasites as there are species of birds. This is in sharp contrast to the approximately 175 parasite species described by traditional methods based on morphology using light microscopy. Until now it has not been clear to what extent parasite mitochondrial DNA lineage diversity reflects intra- or interspecific variation. We have sequenced part of a fast-evolving nuclear gene, dihydrofolate reductase-thymidylate synthase (DHFR-TS), and demonstrate that most of the parasite mitochondrial DNA lineages are associated with unique gene copies at this locus. Although these parasite lineages sometimes coexist in the same host individual, they apparently do not recombine and could therefore be considered as functionally distinct evolutionary entities, with independent evolutionary potential. Studies examining parasite virulence and host immune systems must consider this remarkable diversity of avian malaria parasites.},
  author       = {Bensch, Staffan and Perez-Tris, Javier and Waldenström, Jonas and Hellgren, Olof},
  issn         = {1558-5646},
  language     = {eng},
  number       = {7},
  pages        = {1617--1621},
  publisher    = {Wiley-Blackwell},
  series       = {Evolution},
  title        = {Linkage between nuclear and mitochondrial DNA sequences in avian malaria parasites: Multiple cases of cryptic speciation?},
  volume       = {58},
  year         = {2004},
}