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Steady-State Diffusion in Complex Amphiphilic Films

Åberg, Christoffer LU (2009)
Abstract
The relation between structure and diffusive transport at steady-state

is investigated theoretically for amphiphilic systems. Amphiphilic

systems typically show a large response to moderate changes in control

parameters, such as temperature, osmotic pressure, and the presence of

cosolvents and cosolutes. Such systems is therefore expected to show a

local response in structure due to the transport process. The structure

of the system is analysed in terms of a local equilibrium description.

The main focus is on systems with the propensity of undergoing an

internal phase separation. In this case there is a particularly strong

coupling between the diffusion... (More)
The relation between structure and diffusive transport at steady-state

is investigated theoretically for amphiphilic systems. Amphiphilic

systems typically show a large response to moderate changes in control

parameters, such as temperature, osmotic pressure, and the presence of

cosolvents and cosolutes. Such systems is therefore expected to show a

local response in structure due to the transport process. The structure

of the system is analysed in terms of a local equilibrium description.

The main focus is on systems with the propensity of undergoing an

internal phase separation. In this case there is a particularly strong

coupling between the diffusion process(es) and the local structure of

the system, which can lead to non-linear behaviour.



Specific applications include diffusive transport through the outermost

layer of human skin, the stratum corneum, where the possibility of a

phase change of the stratum corneum lipids could explain experimental

observations of a non-linear behaviour of the water transport. A model

for the formation of a gradient in pH over the stratum corneum is also

presented in terms of the diffusive transport of water and carbon

dioxide. Another application is film formation at the air-liquid

interface of surfactant-water systems undergoing evaporation. A study

showing that the structure of the surfactant layer lining the alveoli is

functionally beneficial for the diffusive transport of oxygen is also

presented. (Less)
Please use this url to cite or link to this publication:
author
supervisor
opponent
  • Dr Kabalnov, Alexey, Hewlett Packard, San Diego, USA
organization
publishing date
type
Thesis
publication status
published
subject
keywords
film formation, lung surfactant, skin surface pH, stratum corneum, responding membrane, diffusive transport, phase transition
pages
162 pages
defense location
Hörsal C, Kemicentrum
defense date
2009-06-04 10:30
ISBN
978-91-7422-221-0
language
English
LU publication?
yes
id
58bf706d-4929-4977-9a9c-ed7b1dbc006f (old id 1390787)
date added to LUP
2009-05-11 11:15:29
date last changed
2016-09-19 08:45:16
@phdthesis{58bf706d-4929-4977-9a9c-ed7b1dbc006f,
  abstract     = {The relation between structure and diffusive transport at steady-state<br/><br>
is investigated theoretically for amphiphilic systems. Amphiphilic<br/><br>
systems typically show a large response to moderate changes in control<br/><br>
parameters, such as temperature, osmotic pressure, and the presence of<br/><br>
cosolvents and cosolutes. Such systems is therefore expected to show a<br/><br>
local response in structure due to the transport process. The structure<br/><br>
of the system is analysed in terms of a local equilibrium description.<br/><br>
The main focus is on systems with the propensity of undergoing an<br/><br>
internal phase separation. In this case there is a particularly strong<br/><br>
coupling between the diffusion process(es) and the local structure of<br/><br>
the system, which can lead to non-linear behaviour.<br/><br>
<br/><br>
Specific applications include diffusive transport through the outermost<br/><br>
layer of human skin, the stratum corneum, where the possibility of a<br/><br>
phase change of the stratum corneum lipids could explain experimental<br/><br>
observations of a non-linear behaviour of the water transport. A model<br/><br>
for the formation of a gradient in pH over the stratum corneum is also<br/><br>
presented in terms of the diffusive transport of water and carbon<br/><br>
dioxide. Another application is film formation at the air-liquid<br/><br>
interface of surfactant-water systems undergoing evaporation. A study<br/><br>
showing that the structure of the surfactant layer lining the alveoli is<br/><br>
functionally beneficial for the diffusive transport of oxygen is also<br/><br>
presented.},
  author       = {Åberg, Christoffer},
  isbn         = {978-91-7422-221-0},
  keyword      = {film formation,lung surfactant,skin surface pH,stratum corneum,responding membrane,diffusive transport,phase transition},
  language     = {eng},
  pages        = {162},
  school       = {Lund University},
  title        = {Steady-State Diffusion in Complex Amphiphilic Films},
  year         = {2009},
}