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Center of volume and total heart volume variation in healthy subjects and patients before and after coronary bypass surgery.

Carlsson, Marcus LU ; Rosengren, Anders LU ; Ugander, Martin LU ; Ekelund, Ulf LU ; Cain, Peter LU and Arheden, Håkan LU (2005) In Clinical Physiology and Functional Imaging 25(4). p.226-233
Abstract
BACKGROUND: Total heart volume variation (THVV) and center of volume variation (COVV) likely affects the efficiency of cardiac pumping, but no study has determined COVV of the heart throughout the cardiac cycle or the effect of surgery on THVV in adults. Therefore, the purposes of this study were to determine COVV in healthy adults and patients with cardiac failure due to ischemic heart disease (IHD), identify any difference in THVV between these two groups, and determine how these parameters are affected by coronary bypass surgery. METHODS: Six healthy volunteers and eight patients before and after surgery were investigated with cardiovascular magnetic resonance imaging. The atrioventricular plane movement (AVPM), THVV and time resolved... (More)
BACKGROUND: Total heart volume variation (THVV) and center of volume variation (COVV) likely affects the efficiency of cardiac pumping, but no study has determined COVV of the heart throughout the cardiac cycle or the effect of surgery on THVV in adults. Therefore, the purposes of this study were to determine COVV in healthy adults and patients with cardiac failure due to ischemic heart disease (IHD), identify any difference in THVV between these two groups, and determine how these parameters are affected by coronary bypass surgery. METHODS: Six healthy volunteers and eight patients before and after surgery were investigated with cardiovascular magnetic resonance imaging. The atrioventricular plane movement (AVPM), THVV and time resolved three-dimensional coordinates of the center of the cardiac volume (COVV) were measured. RESULTS: COVV followed a loop in 3D space that between the end-points was approximately 2 mm with no difference between healthy subjects and patients before surgery (P = 0.093), although AVPM was significantly lower in patients (P = 0.002). However, after surgery the COVV during the cardiac cycle doubled (P = 0.012) and the increase in THVV was significant (P = 0.050), although of very small magnitude, and the AVPM remained unchanged (P = 0.401). CONCLUSION: COVV and THVV were similar in patients and healthy subjects even though AVPM was lower in the patient population. After surgery, however, COVV doubled despite a very small change in THVV and no change in AVPM. Taken together, the results of this study may provide new insights into the energy expenditure and efficiency of cardiac pumping. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging
volume
25
issue
4
pages
226 - 233
publisher
Wiley Online Library
external identifiers
  • wos:000229956800007
  • pmid:15972025
  • scopus:21644479500
ISSN
1475-0961
DOI
10.1111/j.1475-097X.2005.00617.x
language
English
LU publication?
yes
id
1391cc75-1739-4641-ac59-3c19e272396f (old id 139835)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15972025&query_hl=142
date added to LUP
2007-07-11 09:47:49
date last changed
2017-01-01 04:33:37
@article{1391cc75-1739-4641-ac59-3c19e272396f,
  abstract     = {BACKGROUND: Total heart volume variation (THVV) and center of volume variation (COVV) likely affects the efficiency of cardiac pumping, but no study has determined COVV of the heart throughout the cardiac cycle or the effect of surgery on THVV in adults. Therefore, the purposes of this study were to determine COVV in healthy adults and patients with cardiac failure due to ischemic heart disease (IHD), identify any difference in THVV between these two groups, and determine how these parameters are affected by coronary bypass surgery. METHODS: Six healthy volunteers and eight patients before and after surgery were investigated with cardiovascular magnetic resonance imaging. The atrioventricular plane movement (AVPM), THVV and time resolved three-dimensional coordinates of the center of the cardiac volume (COVV) were measured. RESULTS: COVV followed a loop in 3D space that between the end-points was approximately 2 mm with no difference between healthy subjects and patients before surgery (P = 0.093), although AVPM was significantly lower in patients (P = 0.002). However, after surgery the COVV during the cardiac cycle doubled (P = 0.012) and the increase in THVV was significant (P = 0.050), although of very small magnitude, and the AVPM remained unchanged (P = 0.401). CONCLUSION: COVV and THVV were similar in patients and healthy subjects even though AVPM was lower in the patient population. After surgery, however, COVV doubled despite a very small change in THVV and no change in AVPM. Taken together, the results of this study may provide new insights into the energy expenditure and efficiency of cardiac pumping.},
  author       = {Carlsson, Marcus and Rosengren, Anders and Ugander, Martin and Ekelund, Ulf and Cain, Peter and Arheden, Håkan},
  issn         = {1475-0961},
  language     = {eng},
  number       = {4},
  pages        = {226--233},
  publisher    = {Wiley Online Library},
  series       = {Clinical Physiology and Functional Imaging},
  title        = {Center of volume and total heart volume variation in healthy subjects and patients before and after coronary bypass surgery.},
  url          = {http://dx.doi.org/10.1111/j.1475-097X.2005.00617.x},
  volume       = {25},
  year         = {2005},
}