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Spectral characterization of diffusion with chemical shift resolution: Highly concentrated water-in-oil emulsion.

Lasic, Samo LU ; Åslund, Ingrid LU and Topgaard, Daniel LU (2009) In Journal of Magnetic Resonance 199. p.166-172
Abstract
We present a modulated gradient spin-echo method, which uses a train of sinusoidally shaped gradient pulses separated by 180 degrees radio-frequency (RF) pulses. The RF pulses efficiently refocus chemical shifts and de-phasing due to susceptibility differences, resulting in undistorted, high-resolution diffusion weighted spectra. This allows for the simultaneous spectral characterization of the diffusion of several molecular species with different chemical shifts. The technique is robust against susceptibility artifacts, field inhomogeneity and imperfections in the gradient generating equipment. The feasibility of the technique is demonstrated by measuring the diffusion of water, oil, and water-soluble salt in a highly concentrated... (More)
We present a modulated gradient spin-echo method, which uses a train of sinusoidally shaped gradient pulses separated by 180 degrees radio-frequency (RF) pulses. The RF pulses efficiently refocus chemical shifts and de-phasing due to susceptibility differences, resulting in undistorted, high-resolution diffusion weighted spectra. This allows for the simultaneous spectral characterization of the diffusion of several molecular species with different chemical shifts. The technique is robust against susceptibility artifacts, field inhomogeneity and imperfections in the gradient generating equipment. The feasibility of the technique is demonstrated by measuring the diffusion of water, oil, and water-soluble salt in a highly concentrated water-in-oil emulsion. The diffusion of water and salt reveal precise information about the droplet size distribution below the mum-range. Common droplet size distribution explains both the data for water with finite long-range diffusion and the data for salt with negligible long-range diffusion. The results of water diffusion show that the technique is efficient in deconvolving the effects of molecular exchange between droplets and restricted diffusion within droplets. The effects of water exchange suggest that droplets of different sizes are uniformly distributed within the sample. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Magnetic Resonance
volume
199
pages
166 - 172
publisher
Elsevier
external identifiers
  • wos:000268032700006
  • pmid:19435671
  • scopus:67649441090
ISSN
1096-0856
DOI
10.1016/j.jmr.2009.04.014
language
English
LU publication?
yes
id
20f675ed-339b-4999-b2ce-9592f1ae7c5b (old id 1412391)
date added to LUP
2009-06-11 09:53:39
date last changed
2017-07-02 03:53:58
@article{20f675ed-339b-4999-b2ce-9592f1ae7c5b,
  abstract     = {We present a modulated gradient spin-echo method, which uses a train of sinusoidally shaped gradient pulses separated by 180 degrees radio-frequency (RF) pulses. The RF pulses efficiently refocus chemical shifts and de-phasing due to susceptibility differences, resulting in undistorted, high-resolution diffusion weighted spectra. This allows for the simultaneous spectral characterization of the diffusion of several molecular species with different chemical shifts. The technique is robust against susceptibility artifacts, field inhomogeneity and imperfections in the gradient generating equipment. The feasibility of the technique is demonstrated by measuring the diffusion of water, oil, and water-soluble salt in a highly concentrated water-in-oil emulsion. The diffusion of water and salt reveal precise information about the droplet size distribution below the mum-range. Common droplet size distribution explains both the data for water with finite long-range diffusion and the data for salt with negligible long-range diffusion. The results of water diffusion show that the technique is efficient in deconvolving the effects of molecular exchange between droplets and restricted diffusion within droplets. The effects of water exchange suggest that droplets of different sizes are uniformly distributed within the sample.},
  author       = {Lasic, Samo and Åslund, Ingrid and Topgaard, Daniel},
  issn         = {1096-0856},
  language     = {eng},
  pages        = {166--172},
  publisher    = {Elsevier},
  series       = {Journal of Magnetic Resonance},
  title        = {Spectral characterization of diffusion with chemical shift resolution: Highly concentrated water-in-oil emulsion.},
  url          = {http://dx.doi.org/10.1016/j.jmr.2009.04.014},
  volume       = {199},
  year         = {2009},
}