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Oxidative fragmentation of the bridged beta-triketone core of hyperforin

Verotta, L; Lovaglio, E; Sterner, Olov LU ; Appendino, G and Bombardelli, E (2004) In European Journal of Organic Chemistry 2004(6). p.1193-1197
Abstract
The beta-triketone core of the antidepressant phloroglucinol hyperforin (1) undergoes a series of peroxide-induced oxidative rearrangements leading to compound 5, which is formed by opening of ring A, and compound 6, which is formed by removal of the C-1 carbonyl bridge. A mechanistic rationale for this process is proposed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Organic Chemistry
volume
2004
issue
6
pages
1193 - 1197
publisher
John Wiley & Sons
external identifiers
  • wos:000220360700003
  • scopus:4544345612
ISSN
1434-193X
DOI
10.1002/ejoc.200300568
language
English
LU publication?
yes
id
ab191ba0-ce49-4465-a93c-045b6c51c359 (old id 141246)
date added to LUP
2007-07-10 14:57:57
date last changed
2017-11-05 03:46:30
@article{ab191ba0-ce49-4465-a93c-045b6c51c359,
  abstract     = {The beta-triketone core of the antidepressant phloroglucinol hyperforin (1) undergoes a series of peroxide-induced oxidative rearrangements leading to compound 5, which is formed by opening of ring A, and compound 6, which is formed by removal of the C-1 carbonyl bridge. A mechanistic rationale for this process is proposed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).},
  author       = {Verotta, L and Lovaglio, E and Sterner, Olov and Appendino, G and Bombardelli, E},
  issn         = {1434-193X},
  language     = {eng},
  number       = {6},
  pages        = {1193--1197},
  publisher    = {John Wiley & Sons},
  series       = {European Journal of Organic Chemistry},
  title        = {Oxidative fragmentation of the bridged beta-triketone core of hyperforin},
  url          = {http://dx.doi.org/10.1002/ejoc.200300568},
  volume       = {2004},
  year         = {2004},
}