Oxidative fragmentation of the bridged beta-triketone core of hyperforin
(2004) In European Journal of Organic Chemistry 2004(6). p.1193-1197- Abstract
- The beta-triketone core of the antidepressant phloroglucinol hyperforin (1) undergoes a series of peroxide-induced oxidative rearrangements leading to compound 5, which is formed by opening of ring A, and compound 6, which is formed by removal of the C-1 carbonyl bridge. A mechanistic rationale for this process is proposed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/141246
- author
- Verotta, L ; Lovaglio, E ; Sterner, Olov LU ; Appendino, G and Bombardelli, E
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Organic Chemistry
- volume
- 2004
- issue
- 6
- pages
- 1193 - 1197
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000220360700003
- scopus:4544345612
- ISSN
- 1434-193X
- DOI
- 10.1002/ejoc.200300568
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
- id
- ab191ba0-ce49-4465-a93c-045b6c51c359 (old id 141246)
- date added to LUP
- 2016-04-01 12:28:21
- date last changed
- 2022-03-06 00:00:22
@article{ab191ba0-ce49-4465-a93c-045b6c51c359, abstract = {{The beta-triketone core of the antidepressant phloroglucinol hyperforin (1) undergoes a series of peroxide-induced oxidative rearrangements leading to compound 5, which is formed by opening of ring A, and compound 6, which is formed by removal of the C-1 carbonyl bridge. A mechanistic rationale for this process is proposed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).}}, author = {{Verotta, L and Lovaglio, E and Sterner, Olov and Appendino, G and Bombardelli, E}}, issn = {{1434-193X}}, language = {{eng}}, number = {{6}}, pages = {{1193--1197}}, publisher = {{John Wiley & Sons Inc.}}, series = {{European Journal of Organic Chemistry}}, title = {{Oxidative fragmentation of the bridged beta-triketone core of hyperforin}}, url = {{http://dx.doi.org/10.1002/ejoc.200300568}}, doi = {{10.1002/ejoc.200300568}}, volume = {{2004}}, year = {{2004}}, }