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Molecularly imprinted polymer formats for capillary electrochromatography

Nilsson, Jakob LU ; Spégel, Peter LU and Nilsson, Staffan LU (2004) In Journal of Chromatography. B 804(1). p.3-12
Abstract
The research aimed towards the adaptation of molecularly imprinted polymers (MIPs) to the capillary format and the use of these highly selective matrices for capillary electrochromatography (CEC) is reviewed in this article. The MIP is prepared by incorporation of a template molecule into a polymerization protocol. After polymerization and extraction of the template from the resulting polymer a highly selective material with recognition cavities complementary to the template in size, shape and chemical functionality is obtained. MIPs have been used as recognition elements in several different analytical techniques. In combination with CEC a novel separation system with a unique selectivity towards a predetermined target (the template) is... (More)
The research aimed towards the adaptation of molecularly imprinted polymers (MIPs) to the capillary format and the use of these highly selective matrices for capillary electrochromatography (CEC) is reviewed in this article. The MIP is prepared by incorporation of a template molecule into a polymerization protocol. After polymerization and extraction of the template from the resulting polymer a highly selective material with recognition cavities complementary to the template in size, shape and chemical functionality is obtained. MIPs have been used as recognition elements in several different analytical techniques. In combination with CEC a novel separation system with a unique selectivity towards a predetermined target (the template) is achieved. The merge of molecular imprinting technology (MIT) and CEC have introduced several interesting polymer formats, due to the adaptation of the MIP to the miniaturized capillary format. The polymer formats can be classified according to their preparation protocols and appearance into three conceptually different categories, i.e. the monolith, the coating and the nanoparticles. The preparation protocols, characteristics and applications of these formats will be discussed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Molecularly imprinted polymers, Reviews
in
Journal of Chromatography. B
volume
804
issue
1
pages
3 - 12
publisher
Elsevier
external identifiers
  • pmid:15093153
  • wos:000220939100002
  • scopus:1842665820
ISSN
1873-376X
DOI
10.1016/j.jchromb.2003.12.036
language
English
LU publication?
yes
id
de568d6f-dd78-41fb-b727-ce72c47ca2bc (old id 141338)
date added to LUP
2007-06-27 13:14:26
date last changed
2017-08-20 03:31:11
@article{de568d6f-dd78-41fb-b727-ce72c47ca2bc,
  abstract     = {The research aimed towards the adaptation of molecularly imprinted polymers (MIPs) to the capillary format and the use of these highly selective matrices for capillary electrochromatography (CEC) is reviewed in this article. The MIP is prepared by incorporation of a template molecule into a polymerization protocol. After polymerization and extraction of the template from the resulting polymer a highly selective material with recognition cavities complementary to the template in size, shape and chemical functionality is obtained. MIPs have been used as recognition elements in several different analytical techniques. In combination with CEC a novel separation system with a unique selectivity towards a predetermined target (the template) is achieved. The merge of molecular imprinting technology (MIT) and CEC have introduced several interesting polymer formats, due to the adaptation of the MIP to the miniaturized capillary format. The polymer formats can be classified according to their preparation protocols and appearance into three conceptually different categories, i.e. the monolith, the coating and the nanoparticles. The preparation protocols, characteristics and applications of these formats will be discussed.},
  author       = {Nilsson, Jakob and Spégel, Peter and Nilsson, Staffan},
  issn         = {1873-376X},
  keyword      = {Molecularly imprinted polymers,Reviews},
  language     = {eng},
  number       = {1},
  pages        = {3--12},
  publisher    = {Elsevier},
  series       = {Journal of Chromatography. B},
  title        = {Molecularly imprinted polymer formats for capillary electrochromatography},
  url          = {http://dx.doi.org/10.1016/j.jchromb.2003.12.036},
  volume       = {804},
  year         = {2004},
}