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Differences in genetic and transcriptional organization of the glpTQ operons between Haemophilus influenzae type b and nontypeable strains

Song, Xin-Ming and Janson, Håkan LU (2003) In Journal of Bacteriology 185(24). p.7285-7290
Abstract
The glpTQ operon of Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) strains is highly conserved, except for a 1.4-kb glpTQ intergenic region that was found in most Hib strains. The presence of this intergenic region results in divergent glpTQ transcriptional profiles for Hib and NTHi where Hib strains appear to have evolved an alternative promoter for glpQ expression. Based on the intergenic region's low G+C content, we speculate that this DNA fragment was acquired by lateral transfer.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Bacteriology
volume
185
issue
24
pages
7285 - 7290
publisher
American Society for Microbiology
external identifiers
  • pmid:14645291
  • wos:000187183300031
  • scopus:0345529060
ISSN
0021-9193
DOI
language
English
LU publication?
yes
id
b73ab4bd-aaf4-44f2-9784-12bc7f038356 (old id 141868)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14645291&query_hl=37
date added to LUP
2007-07-27 09:13:32
date last changed
2018-05-29 10:39:00
@article{b73ab4bd-aaf4-44f2-9784-12bc7f038356,
  abstract     = {The glpTQ operon of Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) strains is highly conserved, except for a 1.4-kb glpTQ intergenic region that was found in most Hib strains. The presence of this intergenic region results in divergent glpTQ transcriptional profiles for Hib and NTHi where Hib strains appear to have evolved an alternative promoter for glpQ expression. Based on the intergenic region's low G+C content, we speculate that this DNA fragment was acquired by lateral transfer.},
  author       = {Song, Xin-Ming and Janson, Håkan},
  issn         = {0021-9193},
  language     = {eng},
  number       = {24},
  pages        = {7285--7290},
  publisher    = {American Society for Microbiology},
  series       = {Journal of Bacteriology},
  title        = {Differences in genetic and transcriptional organization of the glpTQ operons between Haemophilus influenzae type b and nontypeable strains},
  url          = {http://dx.doi.org/},
  volume       = {185},
  year         = {2003},
}