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Alternative oxidase: a defence against metabolic fluctuations?

Rasmusson, Allan LU ; Fernie, Alisdair R and van Dongen, Joost T (2009) In Physiologia Plantarum 137. p.371-382
Abstract
An increasing number of oscillating or fluctuating cellular systems have been recently described following the adaptation of fluorescent technology. In diverse organisms, these variously involve signalling factors, heat production, central metabolism and reactive oxygen species (ROS). In response to many plant stresses and primarily via the influence of ROS, changes in mRNA and protein levels or in vivo activity of alternative oxidase are often observed. However, in several investigations, a lack of correlation between the mRNA, protein and in vivo activity has been evident. This discrepancy has made it questionable whether the induction of alternative oxidase has importance in regulating alternative pathway activity in vivo, or being... (More)
An increasing number of oscillating or fluctuating cellular systems have been recently described following the adaptation of fluorescent technology. In diverse organisms, these variously involve signalling factors, heat production, central metabolism and reactive oxygen species (ROS). In response to many plant stresses and primarily via the influence of ROS, changes in mRNA and protein levels or in vivo activity of alternative oxidase are often observed. However, in several investigations, a lack of correlation between the mRNA, protein and in vivo activity has been evident. This discrepancy has made it questionable whether the induction of alternative oxidase has importance in regulating alternative pathway activity in vivo, or being diagnostic for a role of alternative oxidase in stress tolerance and ROS avoidance. Here, we suggest a role of alternative oxidase in counteracting deleterious short-term metabolic fluctuations, especially under stress conditions. This model emphasizes the importance of peak activity for establishing protein levels and allows an amalgamation of the present status of physiological, cellular and molecular knowledge. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physiologia Plantarum
volume
137
pages
371 - 382
publisher
Wiley Online Library
external identifiers
  • wos:000271975700008
  • scopus:70450267629
ISSN
0031-9317
DOI
10.1111/j.1399-3054.2009.01252.x
language
English
LU publication?
yes
id
0fc44d82-9f3a-45b8-8ee4-e483cf72a304 (old id 1433841)
date added to LUP
2009-07-03 09:13:53
date last changed
2017-11-19 03:42:21
@article{0fc44d82-9f3a-45b8-8ee4-e483cf72a304,
  abstract     = {An increasing number of oscillating or fluctuating cellular systems have been recently described following the adaptation of fluorescent technology. In diverse organisms, these variously involve signalling factors, heat production, central metabolism and reactive oxygen species (ROS). In response to many plant stresses and primarily via the influence of ROS, changes in mRNA and protein levels or in vivo activity of alternative oxidase are often observed. However, in several investigations, a lack of correlation between the mRNA, protein and in vivo activity has been evident. This discrepancy has made it questionable whether the induction of alternative oxidase has importance in regulating alternative pathway activity in vivo, or being diagnostic for a role of alternative oxidase in stress tolerance and ROS avoidance. Here, we suggest a role of alternative oxidase in counteracting deleterious short-term metabolic fluctuations, especially under stress conditions. This model emphasizes the importance of peak activity for establishing protein levels and allows an amalgamation of the present status of physiological, cellular and molecular knowledge.},
  author       = {Rasmusson, Allan and Fernie, Alisdair R and van Dongen, Joost T},
  issn         = {0031-9317},
  language     = {eng},
  pages        = {371--382},
  publisher    = {Wiley Online Library},
  series       = {Physiologia Plantarum},
  title        = {Alternative oxidase: a defence against metabolic fluctuations?},
  url          = {http://dx.doi.org/10.1111/j.1399-3054.2009.01252.x},
  volume       = {137},
  year         = {2009},
}