Advanced

A population-based cohort study on sun habits and endometrial cancer.

Epstein, Elisabeth LU ; Lindqvist, Pelle LU ; Geppert, Barbara LU and Olsson, H (2009) In British Journal of Cancer 101. p.537-540
Abstract
Background:No large cohort study has examined the risk of endometrial cancer in relation to sun exposure.Methods:A population-based cohort study of 29 508 women who answered a questionnaire in 1990-92, of whom 24 098 responded to a follow-up enquiry in 2000-02. They were followed for an average of 15.5 years.Results:Among the 17 822 postmenopausal women included, 166 cases of endometrial cancer were diagnosed. We used a multivariate Cox regression analysis adjusting for age and other selected demographic variables to determine the risk of endometrial cancer. Women using sun beds >3 times per year reduced their hazard risk (HR) by 40% (0.6, 95% confidence interval (CI) 0.4-0.9) or by 50% when adjusting for body mass index or physical... (More)
Background:No large cohort study has examined the risk of endometrial cancer in relation to sun exposure.Methods:A population-based cohort study of 29 508 women who answered a questionnaire in 1990-92, of whom 24 098 responded to a follow-up enquiry in 2000-02. They were followed for an average of 15.5 years.Results:Among the 17 822 postmenopausal women included, 166 cases of endometrial cancer were diagnosed. We used a multivariate Cox regression analysis adjusting for age and other selected demographic variables to determine the risk of endometrial cancer. Women using sun beds >3 times per year reduced their hazard risk (HR) by 40% (0.6, 95% confidence interval (CI) 0.4-0.9) or by 50% when adjusting for body mass index or physical activity (HR 0.5, 95% CI 0.3-0.9), and those women who were sunbathing during summer reduced their risk by 20% (HR 0.8 95% CI 0.5-1.5) compared with women who did not expose themselves to the sun or to artificial sun (i.e., sun beds).Conclusion:Exposure to artificial sun by the use of sun beds >3 times per year was associated with a 40% reduction in the risk of endometrial cancer, probably by improving the vitamin D levels during winter.British Journal of Cancer advance online publication, 23 June 2009; doi:10.1038/sj.bjc.6605149 www.bjcancer.com. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Cancer
volume
101
pages
537 - 540
publisher
Nature Publishing Group
external identifiers
  • wos:000268439500026
  • pmid:19550419
  • scopus:68149181876
ISSN
1532-1827
DOI
10.1038/sj.bjc.6605149
language
English
LU publication?
yes
id
f9807fe6-83e1-46d7-a197-5c0db8909657 (old id 1433958)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19550419?dopt=Abstract
date added to LUP
2009-07-06 10:37:13
date last changed
2017-11-19 04:17:31
@article{f9807fe6-83e1-46d7-a197-5c0db8909657,
  abstract     = {Background:No large cohort study has examined the risk of endometrial cancer in relation to sun exposure.Methods:A population-based cohort study of 29 508 women who answered a questionnaire in 1990-92, of whom 24 098 responded to a follow-up enquiry in 2000-02. They were followed for an average of 15.5 years.Results:Among the 17 822 postmenopausal women included, 166 cases of endometrial cancer were diagnosed. We used a multivariate Cox regression analysis adjusting for age and other selected demographic variables to determine the risk of endometrial cancer. Women using sun beds >3 times per year reduced their hazard risk (HR) by 40% (0.6, 95% confidence interval (CI) 0.4-0.9) or by 50% when adjusting for body mass index or physical activity (HR 0.5, 95% CI 0.3-0.9), and those women who were sunbathing during summer reduced their risk by 20% (HR 0.8 95% CI 0.5-1.5) compared with women who did not expose themselves to the sun or to artificial sun (i.e., sun beds).Conclusion:Exposure to artificial sun by the use of sun beds >3 times per year was associated with a 40% reduction in the risk of endometrial cancer, probably by improving the vitamin D levels during winter.British Journal of Cancer advance online publication, 23 June 2009; doi:10.1038/sj.bjc.6605149 www.bjcancer.com.},
  author       = {Epstein, Elisabeth and Lindqvist, Pelle and Geppert, Barbara and Olsson, H},
  issn         = {1532-1827},
  language     = {eng},
  pages        = {537--540},
  publisher    = {Nature Publishing Group},
  series       = {British Journal of Cancer},
  title        = {A population-based cohort study on sun habits and endometrial cancer.},
  url          = {http://dx.doi.org/10.1038/sj.bjc.6605149},
  volume       = {101},
  year         = {2009},
}