Interatrial right-to-left conduction in patients with paroxysmal atrial fibrillation
(2009) In Journal of Interventional Cardiac Electrophysiology 25(2). p.117-122- Abstract
- We wanted to illustrate the right-to-left impulse propagation routes during sinus in patients with paroxysmal atrial fibrillation (PAF), as alterations in conduction patterns have been linked to the pathogenesis of PAF, and as no large patient materials have been published. Patients underwent 3-D electroanatomical contact mapping prior to catheter ablation. The site of the earliest left atrial (LA) activation was determined. Three different interatrial routes were identified, either as solitary pathways (36/50 patients, 72%) or in their combinations (14/50). Bachmann's bundle (BB) was involved in the majority of the cases with solitary routes (25/36). More seldom, impulse propagation occurred near the oval fossa (FO) (7/36) or the coronary... (More)
- We wanted to illustrate the right-to-left impulse propagation routes during sinus in patients with paroxysmal atrial fibrillation (PAF), as alterations in conduction patterns have been linked to the pathogenesis of PAF, and as no large patient materials have been published. Patients underwent 3-D electroanatomical contact mapping prior to catheter ablation. The site of the earliest left atrial (LA) activation was determined. Three different interatrial routes were identified, either as solitary pathways (36/50 patients, 72%) or in their combinations (14/50). Bachmann's bundle (BB) was involved in the majority of the cases with solitary routes (25/36). More seldom, impulse propagation occurred near the oval fossa (FO) (7/36) or the coronary sinus ostium (4/36). In patients with combined routes, both the BB (10/14) and FO routes (11/14) were included in most cases. In PAF patients, LA can be activated during sinus rhythm through three distinct connections, either encompassing a single route or via any combination of these connections. In one third, the earliest LA activation occurs outside BB. The knowledge of the propagation patterns may give insight into the pathophysiology of PAF and into refining ablation therapy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1463088
- author
- Tapanainen, Jari M. ; Jurkko, Raija ; Holmqvist, Fredrik LU ; Husser, Daniela ; Kongstad Rasmussen, Ole LU ; Makijarvi, Markku ; Toivonen, Lauri and Platonov, Pyotr LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Catheter ablation, Interatrial conduction, Atrial fibrillation, Electroanatomic mapping, Sinus rhythm
- in
- Journal of Interventional Cardiac Electrophysiology
- volume
- 25
- issue
- 2
- pages
- 117 - 122
- publisher
- Springer
- external identifiers
-
- wos:000267683500006
- scopus:67651108951
- ISSN
- 1572-8595
- DOI
- 10.1007/s10840-008-9359-2
- language
- English
- LU publication?
- yes
- id
- 125ad2c6-8286-47fc-9610-3278ba4ea2be (old id 1463088)
- date added to LUP
- 2016-04-01 12:33:34
- date last changed
- 2022-03-29 02:30:11
@article{125ad2c6-8286-47fc-9610-3278ba4ea2be, abstract = {{We wanted to illustrate the right-to-left impulse propagation routes during sinus in patients with paroxysmal atrial fibrillation (PAF), as alterations in conduction patterns have been linked to the pathogenesis of PAF, and as no large patient materials have been published. Patients underwent 3-D electroanatomical contact mapping prior to catheter ablation. The site of the earliest left atrial (LA) activation was determined. Three different interatrial routes were identified, either as solitary pathways (36/50 patients, 72%) or in their combinations (14/50). Bachmann's bundle (BB) was involved in the majority of the cases with solitary routes (25/36). More seldom, impulse propagation occurred near the oval fossa (FO) (7/36) or the coronary sinus ostium (4/36). In patients with combined routes, both the BB (10/14) and FO routes (11/14) were included in most cases. In PAF patients, LA can be activated during sinus rhythm through three distinct connections, either encompassing a single route or via any combination of these connections. In one third, the earliest LA activation occurs outside BB. The knowledge of the propagation patterns may give insight into the pathophysiology of PAF and into refining ablation therapy.}}, author = {{Tapanainen, Jari M. and Jurkko, Raija and Holmqvist, Fredrik and Husser, Daniela and Kongstad Rasmussen, Ole and Makijarvi, Markku and Toivonen, Lauri and Platonov, Pyotr}}, issn = {{1572-8595}}, keywords = {{Catheter ablation; Interatrial conduction; Atrial fibrillation; Electroanatomic mapping; Sinus rhythm}}, language = {{eng}}, number = {{2}}, pages = {{117--122}}, publisher = {{Springer}}, series = {{Journal of Interventional Cardiac Electrophysiology}}, title = {{Interatrial right-to-left conduction in patients with paroxysmal atrial fibrillation}}, url = {{http://dx.doi.org/10.1007/s10840-008-9359-2}}, doi = {{10.1007/s10840-008-9359-2}}, volume = {{25}}, year = {{2009}}, }