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Review of cell and particle trapping in microfluidic systems.

Nilsson, Johan LU ; Evander, Mikael LU ; Hammarström, Björn LU and Laurell, Thomas LU (2009) In Analytica Chimica Acta 649(2). p.141-157
Abstract
The ability to obtain ideal conditions for well-defined chemical microenvironments and controlled temporal chemical and/or thermal variations holds promise of high-resolution cell response studies, cell-cell interactions or e.g. proliferation conditions for stem cells. It is a major motivation for the rapid increase of lab-on-a-chip based cell biology research. In view of this, new chip-integrated technologies are at an increasing rate being presented to the research community as potential tools to offer spatial control and manipulation of cells in microfluidic systems. This is becoming a key area of interest in the emerging lab-on-a-chip based cell biology research field. This review focuses on the different technical approaches presented... (More)
The ability to obtain ideal conditions for well-defined chemical microenvironments and controlled temporal chemical and/or thermal variations holds promise of high-resolution cell response studies, cell-cell interactions or e.g. proliferation conditions for stem cells. It is a major motivation for the rapid increase of lab-on-a-chip based cell biology research. In view of this, new chip-integrated technologies are at an increasing rate being presented to the research community as potential tools to offer spatial control and manipulation of cells in microfluidic systems. This is becoming a key area of interest in the emerging lab-on-a-chip based cell biology research field. This review focuses on the different technical approaches presented to enable trapping of particles and cells in microfluidic system. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Analytica Chimica Acta
volume
649
issue
2
pages
141 - 157
publisher
Elsevier
external identifiers
  • wos:000269652800002
  • pmid:19699390
  • scopus:68749084814
ISSN
1873-4324
DOI
10.1016/j.aca.2009.07.017
language
English
LU publication?
yes
id
93874d45-667c-410c-a37f-9559b1c3b217 (old id 1469484)
date added to LUP
2009-09-08 14:23:29
date last changed
2017-12-10 04:11:09
@article{93874d45-667c-410c-a37f-9559b1c3b217,
  abstract     = {The ability to obtain ideal conditions for well-defined chemical microenvironments and controlled temporal chemical and/or thermal variations holds promise of high-resolution cell response studies, cell-cell interactions or e.g. proliferation conditions for stem cells. It is a major motivation for the rapid increase of lab-on-a-chip based cell biology research. In view of this, new chip-integrated technologies are at an increasing rate being presented to the research community as potential tools to offer spatial control and manipulation of cells in microfluidic systems. This is becoming a key area of interest in the emerging lab-on-a-chip based cell biology research field. This review focuses on the different technical approaches presented to enable trapping of particles and cells in microfluidic system.},
  author       = {Nilsson, Johan and Evander, Mikael and Hammarström, Björn and Laurell, Thomas},
  issn         = {1873-4324},
  language     = {eng},
  number       = {2},
  pages        = {141--157},
  publisher    = {Elsevier},
  series       = {Analytica Chimica Acta},
  title        = {Review of cell and particle trapping in microfluidic systems.},
  url          = {http://dx.doi.org/10.1016/j.aca.2009.07.017},
  volume       = {649},
  year         = {2009},
}